IL-33-experienced group 2 innate lymphoid cells in the lung are poised to enhance type 2 inflammation selectively in adult female mice

IL-33-experienced group 2 innate lymphoid cells in the lung are poised to enhance type 2 inflammation selectively in adult female mice

Abstract While Th2 adaptive immunity has long been considered to orchestrate type 2 inflammation in the allergic lung, group 2 innate lymphoid cells (ILC2s), with the ability to produce a similar profile of type 2 cytokines, likely participate in lung inflammation in allergic asthma. ILC2s are also...

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Bibliographic Details
Main Authors: Haya Aldossary, Rami Karkout, Katalina Couto, Lydia Labrie, Elizabeth D. Fixman
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Respiratory Research
Subjects:
IL-33
IL-25
ILC2
Trained immunity
Th2 adaptive immunity
Lung inflammation
Online Access:https://doi.org/10.1186/s12931-024-03043-2
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