Cutaneous paraneoplastic presentation of colon cancer in a patient with history of ureterosigmoidostomy

Abstract. Ureterosigmoidostomy was commonly utilized as a procedure for continent urinary diversion. However, ureterosigmoidostomy is associated with complications such as infection, electrolyte disturbances, and neoplasia development. A 40-year-old Caucasian male presented with acute left flank pai...

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Main Authors: Mike Swindle, Austin Fernstrum, Timmie Sharma, Kirtishri Mishra, Laura Bukavina, Megan Prunty, Donald Bodner
Format: Article
Language:English
Published: Wolters Kluwer Health 2024-12-01
Series:Current Urology
Online Access:http://journals.lww.com/10.1097/CU9.0000000000000045
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author Mike Swindle
Austin Fernstrum
Timmie Sharma
Kirtishri Mishra
Laura Bukavina
Megan Prunty
Donald Bodner
author_facet Mike Swindle
Austin Fernstrum
Timmie Sharma
Kirtishri Mishra
Laura Bukavina
Megan Prunty
Donald Bodner
author_sort Mike Swindle
collection DOAJ
description Abstract. Ureterosigmoidostomy was commonly utilized as a procedure for continent urinary diversion. However, ureterosigmoidostomy is associated with complications such as infection, electrolyte disturbances, and neoplasia development. A 40-year-old Caucasian male presented with acute left flank pain. Past medical history was significant for bladder exstrophy for which ureterosigmoidostomy urinary diversion was performed during childhood. On physical exam, multiple circular erythematous patches were scattered across the forearms that had been presented for 2 years. Cross-sectional imaging demonnttated an ill-defined mass at the site of ureteral implantation with associated severe left hydroureteronephrosis. Endoscopy revealed a mass at the site of ureteral implantation and biopsy demonstrated invasive, poorly differentiated adenocarcinoma. The dermatosis was diagnosed as interstitial granulomatous dermatitis, a rare inflammatory skin condition associated with underlying autoimmune disease or malignancy. Patient elected operative management with left nephrectomy, sigmoidectomy, and ileal conduit diversion. Ihis case demonnttates a rare presentation of cutaneous paraneoplastic syndrome after development of colon cancer after ureterosigmoidostomy. Ureterooolonic urinary diversion has a demonnttaaie risk of neoplasia development at the anastomotic site, requiring routine endoscopic surveillance.
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spelling doaj-art-b348a1edb0a044ca81506063366e277e2025-08-20T02:16:10ZengWolters Kluwer HealthCurrent Urology1661-76491661-76572024-12-0118434734910.1097/CU9.0000000000000045202412000-00020Cutaneous paraneoplastic presentation of colon cancer in a patient with history of ureterosigmoidostomyMike Swindle0Austin Fernstrum1Timmie Sharma2Kirtishri Mishra3Laura Bukavina4Megan Prunty5Donald Bodner6a Case Western Reserve University School of Medicine, Cleveland, OH, USAa Case Western Reserve University School of Medicine, Cleveland, OH, USAa Case Western Reserve University School of Medicine, Cleveland, OH, USAa Case Western Reserve University School of Medicine, Cleveland, OH, USAa Case Western Reserve University School of Medicine, Cleveland, OH, USAa Case Western Reserve University School of Medicine, Cleveland, OH, USAa Case Western Reserve University School of Medicine, Cleveland, OH, USAAbstract. Ureterosigmoidostomy was commonly utilized as a procedure for continent urinary diversion. However, ureterosigmoidostomy is associated with complications such as infection, electrolyte disturbances, and neoplasia development. A 40-year-old Caucasian male presented with acute left flank pain. Past medical history was significant for bladder exstrophy for which ureterosigmoidostomy urinary diversion was performed during childhood. On physical exam, multiple circular erythematous patches were scattered across the forearms that had been presented for 2 years. Cross-sectional imaging demonnttated an ill-defined mass at the site of ureteral implantation with associated severe left hydroureteronephrosis. Endoscopy revealed a mass at the site of ureteral implantation and biopsy demonstrated invasive, poorly differentiated adenocarcinoma. The dermatosis was diagnosed as interstitial granulomatous dermatitis, a rare inflammatory skin condition associated with underlying autoimmune disease or malignancy. Patient elected operative management with left nephrectomy, sigmoidectomy, and ileal conduit diversion. Ihis case demonnttates a rare presentation of cutaneous paraneoplastic syndrome after development of colon cancer after ureterosigmoidostomy. Ureterooolonic urinary diversion has a demonnttaaie risk of neoplasia development at the anastomotic site, requiring routine endoscopic surveillance.http://journals.lww.com/10.1097/CU9.0000000000000045
spellingShingle Mike Swindle
Austin Fernstrum
Timmie Sharma
Kirtishri Mishra
Laura Bukavina
Megan Prunty
Donald Bodner
Cutaneous paraneoplastic presentation of colon cancer in a patient with history of ureterosigmoidostomy
Current Urology
title Cutaneous paraneoplastic presentation of colon cancer in a patient with history of ureterosigmoidostomy
title_full Cutaneous paraneoplastic presentation of colon cancer in a patient with history of ureterosigmoidostomy
title_fullStr Cutaneous paraneoplastic presentation of colon cancer in a patient with history of ureterosigmoidostomy
title_full_unstemmed Cutaneous paraneoplastic presentation of colon cancer in a patient with history of ureterosigmoidostomy
title_short Cutaneous paraneoplastic presentation of colon cancer in a patient with history of ureterosigmoidostomy
title_sort cutaneous paraneoplastic presentation of colon cancer in a patient with history of ureterosigmoidostomy
url http://journals.lww.com/10.1097/CU9.0000000000000045
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