Evolutionary trajectory estimation via replication simulation of coronavirus spike gene based on random mutation and similarity-based selection

Evolutionary trajectory estimation via replication simulation of coronavirus spike gene based on random mutation and similarity-based selection

Viruses exhibit rapid evolutionary dynamics through random mutations and selection, driving their adaptation and cross-species transmission. To investigate these mechanisms, we designed a simulation framework with a graphical user interface (GUI), implementing random mutation and similarity-based se...

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Bibliographic Details
Main Authors: Min Chan Kim, Hye Ji Jung, Seong Sik Jang, Van Thi Lo, Hye Kwon Kim
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Virus evolution
Random mutation
Similarity
Selection
Evolutionary trajectory
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037025003356
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