Studies on Novel N4-[4,6-Diaryl-2-pyrimidinyl]-7-chloro-4-quinolinamine and their Microbicidal Efficacy
The required chalcones 1a-h were prepared by reaction of substituted acetophenone with different aryl aldehyde, which in turn treated with guanidine nitrate, yielded 4-(substituted phenyl)-6-(substituted phenyl)-2-pyrimidinamine 2a-h. Novel pyrimidine quinoline clubbed molecules 3a-h have been prepa...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2009-01-01
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| Series: | E-Journal of Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2009/301426 |
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| _version_ | 1832556405911977984 |
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| author | Arvind G. Mehta Avnish A. Patel |
| author_facet | Arvind G. Mehta Avnish A. Patel |
| author_sort | Arvind G. Mehta |
| collection | DOAJ |
| description | The required chalcones 1a-h were prepared by reaction of substituted acetophenone with different aryl aldehyde, which in turn treated with guanidine nitrate, yielded 4-(substituted phenyl)-6-(substituted phenyl)-2-pyrimidinamine 2a-h. Novel pyrimidine quinoline clubbed molecules 3a-h have been prepared by reaction of 2a-h with 4,7-dichloroquinoline. All the compounds were characterized by elemental analysis and spectral studies. The newly synthesized compounds were evaluated for their antibacterial and antifungal activity. |
| format | Article |
| id | doaj-art-b34166d5c30f41f783123ac67b5bf61a |
| institution | Kabale University |
| issn | 0973-4945 2090-9810 |
| language | English |
| publishDate | 2009-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | E-Journal of Chemistry |
| spelling | doaj-art-b34166d5c30f41f783123ac67b5bf61a2025-02-03T05:45:29ZengWileyE-Journal of Chemistry0973-49452090-98102009-01-016S1S406S41210.1155/2009/301426Studies on Novel N4-[4,6-Diaryl-2-pyrimidinyl]-7-chloro-4-quinolinamine and their Microbicidal EfficacyArvind G. Mehta0Avnish A. Patel1Department of Chemistry, Sir P. T. Sarvajanik College of Science, Veer Narmad South Gujarat University, Surat-395017, Gujarat, IndiaDepartment of Chemistry, Sir P. T. Sarvajanik College of Science, Veer Narmad South Gujarat University, Surat-395017, Gujarat, IndiaThe required chalcones 1a-h were prepared by reaction of substituted acetophenone with different aryl aldehyde, which in turn treated with guanidine nitrate, yielded 4-(substituted phenyl)-6-(substituted phenyl)-2-pyrimidinamine 2a-h. Novel pyrimidine quinoline clubbed molecules 3a-h have been prepared by reaction of 2a-h with 4,7-dichloroquinoline. All the compounds were characterized by elemental analysis and spectral studies. The newly synthesized compounds were evaluated for their antibacterial and antifungal activity.http://dx.doi.org/10.1155/2009/301426 |
| spellingShingle | Arvind G. Mehta Avnish A. Patel Studies on Novel N4-[4,6-Diaryl-2-pyrimidinyl]-7-chloro-4-quinolinamine and their Microbicidal Efficacy E-Journal of Chemistry |
| title | Studies on Novel N4-[4,6-Diaryl-2-pyrimidinyl]-7-chloro-4-quinolinamine and their Microbicidal Efficacy |
| title_full | Studies on Novel N4-[4,6-Diaryl-2-pyrimidinyl]-7-chloro-4-quinolinamine and their Microbicidal Efficacy |
| title_fullStr | Studies on Novel N4-[4,6-Diaryl-2-pyrimidinyl]-7-chloro-4-quinolinamine and their Microbicidal Efficacy |
| title_full_unstemmed | Studies on Novel N4-[4,6-Diaryl-2-pyrimidinyl]-7-chloro-4-quinolinamine and their Microbicidal Efficacy |
| title_short | Studies on Novel N4-[4,6-Diaryl-2-pyrimidinyl]-7-chloro-4-quinolinamine and their Microbicidal Efficacy |
| title_sort | studies on novel n4 4 6 diaryl 2 pyrimidinyl 7 chloro 4 quinolinamine and their microbicidal efficacy |
| url | http://dx.doi.org/10.1155/2009/301426 |
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