Magnetic Resonance-Guided Diagnosis of Spontaneous Intracranial Hypotension in a Middle-Aged Woman

Spontaneous intracranial hypotension (SIH) is a rare condition caused by a cerebrospinal fluid (CSF) leak. It is diagnosed by clinical features that include an orthostatic headache combined with imaging findings demonstrating intracranial hypotension and a CSF leak. We present the case of a 45-year-...

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Main Authors: Jordan Hughes, Briana Chavez
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Case Reports in Neurological Medicine
Online Access:http://dx.doi.org/10.1155/2022/4438923
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author Jordan Hughes
Briana Chavez
author_facet Jordan Hughes
Briana Chavez
author_sort Jordan Hughes
collection DOAJ
description Spontaneous intracranial hypotension (SIH) is a rare condition caused by a cerebrospinal fluid (CSF) leak. It is diagnosed by clinical features that include an orthostatic headache combined with imaging findings demonstrating intracranial hypotension and a CSF leak. We present the case of a 45-year-old woman with an orthostatic headache who was found to have a sagging brain with a downward-displaced cerebellum and pachymeningeal enhancement with gadolinium contrast. This was initially misidentified as a Chiari I malformation, but the constellation of symptoms and MRI findings were later recognized as characteristic of SIH. Diagnosis of SIH and a CSF leak was confirmed with CT myelography. She was treated with a nontarget epidural blood patch, and her symptoms resolved. An orthostatic headache, a sagging brain, and pachymeningeal enhancement on MRI are highly specific for SIH, raising suspicion for this uncommon and often missed diagnosis.
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spelling doaj-art-b33a5cfdd4874287814f9c0ec6be0aea2025-08-20T02:23:27ZengWileyCase Reports in Neurological Medicine2090-66762022-01-01202210.1155/2022/4438923Magnetic Resonance-Guided Diagnosis of Spontaneous Intracranial Hypotension in a Middle-Aged WomanJordan Hughes0Briana Chavez1Mountainview Regional Medical CenterBurrell College of Osteopathic MedicineSpontaneous intracranial hypotension (SIH) is a rare condition caused by a cerebrospinal fluid (CSF) leak. It is diagnosed by clinical features that include an orthostatic headache combined with imaging findings demonstrating intracranial hypotension and a CSF leak. We present the case of a 45-year-old woman with an orthostatic headache who was found to have a sagging brain with a downward-displaced cerebellum and pachymeningeal enhancement with gadolinium contrast. This was initially misidentified as a Chiari I malformation, but the constellation of symptoms and MRI findings were later recognized as characteristic of SIH. Diagnosis of SIH and a CSF leak was confirmed with CT myelography. She was treated with a nontarget epidural blood patch, and her symptoms resolved. An orthostatic headache, a sagging brain, and pachymeningeal enhancement on MRI are highly specific for SIH, raising suspicion for this uncommon and often missed diagnosis.http://dx.doi.org/10.1155/2022/4438923
spellingShingle Jordan Hughes
Briana Chavez
Magnetic Resonance-Guided Diagnosis of Spontaneous Intracranial Hypotension in a Middle-Aged Woman
Case Reports in Neurological Medicine
title Magnetic Resonance-Guided Diagnosis of Spontaneous Intracranial Hypotension in a Middle-Aged Woman
title_full Magnetic Resonance-Guided Diagnosis of Spontaneous Intracranial Hypotension in a Middle-Aged Woman
title_fullStr Magnetic Resonance-Guided Diagnosis of Spontaneous Intracranial Hypotension in a Middle-Aged Woman
title_full_unstemmed Magnetic Resonance-Guided Diagnosis of Spontaneous Intracranial Hypotension in a Middle-Aged Woman
title_short Magnetic Resonance-Guided Diagnosis of Spontaneous Intracranial Hypotension in a Middle-Aged Woman
title_sort magnetic resonance guided diagnosis of spontaneous intracranial hypotension in a middle aged woman
url http://dx.doi.org/10.1155/2022/4438923
work_keys_str_mv AT jordanhughes magneticresonanceguideddiagnosisofspontaneousintracranialhypotensioninamiddleagedwoman
AT brianachavez magneticresonanceguideddiagnosisofspontaneousintracranialhypotensioninamiddleagedwoman