HIV-associated lymphomas

A steady worldwide increase in the number of people living with HIV (PLHIV) and diagnostic methods requires a separate review of patient-specific nosologies, including lymphoproliferative diseases, some of which are directly associated with the virus due to its oncogenic effect and those that do not...

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Main Authors: G. A. Dudina, Ch. K. Mabudzada, A. A. Ogannisyan, V. N. Nemikin
Format: Article
Language:English
Published: Bashkir State Medical University 2023-01-01
Series:Креативная хирургия и онкология
Subjects:
Online Access:https://www.surgonco.ru/jour/article/view/739
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author G. A. Dudina
Ch. K. Mabudzada
A. A. Ogannisyan
V. N. Nemikin
author_facet G. A. Dudina
Ch. K. Mabudzada
A. A. Ogannisyan
V. N. Nemikin
author_sort G. A. Dudina
collection DOAJ
description A steady worldwide increase in the number of people living with HIV (PLHIV) and diagnostic methods requires a separate review of patient-specific nosologies, including lymphoproliferative diseases, some of which are directly associated with the virus due to its oncogenic effect and those that do not relate directly to HIV but introduce nuances to diagnostic and therapeutic approaches when a patient is HIV-positive. Towards this, the paper generally reviews lymphomas in PLHIV, presents the WHO classification of HIV-associated lymphomas, describes a contemporary view of the known mechanisms of pathogenesis, including the role of opportunistic infections, and general principles of diagnostic and therapeutic tactics, provides recommendations on modifying the doses of chemotherapy correlated with the immune status and on preventing CNS involvement. Specific types of lymphoma (Burkitt’s lymphoma, diff use large B-cell lymphoma) are considered separately, including those most frequently associated with patients living with HIV (primary effusion lymphoma, plasmablastic lymphoma, primary central nervous system lymphoma), but rare in the uninfected population.
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institution Kabale University
issn 2076-3093
2307-0501
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publisher Bashkir State Medical University
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series Креативная хирургия и онкология
spelling doaj-art-b335dacf6edd416db0eb98af47cfe8032025-08-20T03:57:27ZengBashkir State Medical UniversityКреативная хирургия и онкология2076-30932307-05012023-01-0112432032710.24060/2076-3093-2022-12-4-320-327504HIV-associated lymphomasG. A. Dudina0Ch. K. Mabudzada1A. A. Ogannisyan2V. N. Nemikin3Loginov Moscow Clinical Scientific Center; Pirogov Russian National Research Medical UniversityLoginov Moscow Clinical Scientific CenterLoginov Moscow Clinical Scientific CenterLoginov Moscow Clinical Scientific CenterA steady worldwide increase in the number of people living with HIV (PLHIV) and diagnostic methods requires a separate review of patient-specific nosologies, including lymphoproliferative diseases, some of which are directly associated with the virus due to its oncogenic effect and those that do not relate directly to HIV but introduce nuances to diagnostic and therapeutic approaches when a patient is HIV-positive. Towards this, the paper generally reviews lymphomas in PLHIV, presents the WHO classification of HIV-associated lymphomas, describes a contemporary view of the known mechanisms of pathogenesis, including the role of opportunistic infections, and general principles of diagnostic and therapeutic tactics, provides recommendations on modifying the doses of chemotherapy correlated with the immune status and on preventing CNS involvement. Specific types of lymphoma (Burkitt’s lymphoma, diff use large B-cell lymphoma) are considered separately, including those most frequently associated with patients living with HIV (primary effusion lymphoma, plasmablastic lymphoma, primary central nervous system lymphoma), but rare in the uninfected population.https://www.surgonco.ru/jour/article/view/739hivlymphomahiv-associated lymphomaantiretroviral therapyepstein — barr viruscd4+ lymphocyteslymphoproliferative diseasesburkitt lymphomadiff use b-large cell lymphoma
spellingShingle G. A. Dudina
Ch. K. Mabudzada
A. A. Ogannisyan
V. N. Nemikin
HIV-associated lymphomas
Креативная хирургия и онкология
hiv
lymphoma
hiv-associated lymphoma
antiretroviral therapy
epstein — barr virus
cd4+ lymphocytes
lymphoproliferative diseases
burkitt lymphoma
diff use b-large cell lymphoma
title HIV-associated lymphomas
title_full HIV-associated lymphomas
title_fullStr HIV-associated lymphomas
title_full_unstemmed HIV-associated lymphomas
title_short HIV-associated lymphomas
title_sort hiv associated lymphomas
topic hiv
lymphoma
hiv-associated lymphoma
antiretroviral therapy
epstein — barr virus
cd4+ lymphocytes
lymphoproliferative diseases
burkitt lymphoma
diff use b-large cell lymphoma
url https://www.surgonco.ru/jour/article/view/739
work_keys_str_mv AT gadudina hivassociatedlymphomas
AT chkmabudzada hivassociatedlymphomas
AT aaogannisyan hivassociatedlymphomas
AT vnnemikin hivassociatedlymphomas