The causal relationships between mitochondria and six types of cancer: a Mendelian randomization study

The causal relationships between mitochondria and six types of cancer: a Mendelian randomization study

Abstract Background Mitochondria play a multifaceted role in tumorigenesis, influencing energy metabolism, redox balance, and apoptosis. However, whether mitochondrial traits causally affect cancer risk remains unclear. This study aimed to evaluate the potential causal effects of 82 mitochondrial-re...

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Main Authors: Jincheng Tang, Jingting Zhang, Renyi Yang, Hongyao Chen, Xiaopeng Yu, Wei Peng, Puhua Zeng
Format: Article
Language:English
Published: BMC 2025-04-01
Series:BMC Cancer
Subjects:
Mendelian randomization
Mitochondria
Cancers
Causal inference
Online Access:https://doi.org/10.1186/s12885-025-14201-0
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