Early Alpha-Fetoprotein Response Predicts Sustained Tumor Response Following Immune Checkpoint Inhibitors Combined with Targeted Therapy in Liver Cancer

Early Alpha-Fetoprotein Response Predicts Sustained Tumor Response Following Immune Checkpoint Inhibitors Combined with Targeted Therapy in Liver Cancer

<b>Background:</b> Although immune checkpoint inhibitors (ICI) have revolutionized liver cancer treatment, some patients experience early tumor progression after therapy, missing the window for other potential treatments, such as neoadjuvant therapy. Therefore, identifying the predictive...

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Bibliographic Details
Main Authors: Jiahe Tian, Shida Pan, Yilin Wang, Yingying Yu, Siyu Wang, Yingjuan Shen, Luo Yang, Xiaomeng Liu, Qin Qiu, Junqing Luan, Fusheng Wang, Fanping Meng
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Biomedicines
Subjects:
liver cancer
hepatocellular carcinoma (HCC)
immune checkpoint inhibitors (ICI)
alpha-fetoprotein (AFP)
biomarker
progression-free survival (PFS)
Online Access:https://www.mdpi.com/2227-9059/12/12/2769
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