The Impact of Nonsurgical Periodontal Therapy on the Salivary Proteome: A Pilot Study
Conclusions: Salivary proteome analysis revealed a distinct disease-associated protein signature in G2 group, supporting its potential as a noninvasive tool for diagnosis and monitoring of Pd patients. The post-NSPT shifts in protein expression further highlight the effectiveness of periodontal ther...
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| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2025-01-01
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| Series: | International Journal of Dentistry |
| Online Access: | http://dx.doi.org/10.1155/ijod/6655743 |
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| _version_ | 1849239605383004160 |
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| author | Stefania Bergamini Elisa Bellei Valentina Selleri Roberta Salvatori Giulia Micheloni Milena Nasi Marcello Pinti Carlo Bertoldi |
| author_facet | Stefania Bergamini Elisa Bellei Valentina Selleri Roberta Salvatori Giulia Micheloni Milena Nasi Marcello Pinti Carlo Bertoldi |
| author_sort | Stefania Bergamini |
| collection | DOAJ |
| description | Conclusions: Salivary proteome analysis revealed a distinct disease-associated protein signature in G2 group, supporting its potential as a noninvasive tool for diagnosis and monitoring of Pd patients. The post-NSPT shifts in protein expression further highlight the effectiveness of periodontal therapy in modulating inflammatory biomarkers. Future studies on larger cohorts are needed to validate these findings and advance saliva-based proteomics toward personalized periodontal care. |
| format | Article |
| id | doaj-art-b32c1fd515cb477dba27880c552ee5e2 |
| institution | Kabale University |
| issn | 1687-8736 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Dentistry |
| spelling | doaj-art-b32c1fd515cb477dba27880c552ee5e22025-08-20T04:00:54ZengWileyInternational Journal of Dentistry1687-87362025-01-01202510.1155/ijod/6655743The Impact of Nonsurgical Periodontal Therapy on the Salivary Proteome: A Pilot StudyStefania Bergamini0Elisa Bellei1Valentina Selleri2Roberta Salvatori3Giulia Micheloni4Milena Nasi5Marcello Pinti6Carlo Bertoldi7Department of Surgical, MedicalDepartment of Surgical, MedicalDepartment of Life SciencesDepartment of MaternalDepartment of Life SciencesDepartment of Surgical, MedicalDepartment of Life SciencesDepartment of Surgical, MedicalConclusions: Salivary proteome analysis revealed a distinct disease-associated protein signature in G2 group, supporting its potential as a noninvasive tool for diagnosis and monitoring of Pd patients. The post-NSPT shifts in protein expression further highlight the effectiveness of periodontal therapy in modulating inflammatory biomarkers. Future studies on larger cohorts are needed to validate these findings and advance saliva-based proteomics toward personalized periodontal care.http://dx.doi.org/10.1155/ijod/6655743 |
| spellingShingle | Stefania Bergamini Elisa Bellei Valentina Selleri Roberta Salvatori Giulia Micheloni Milena Nasi Marcello Pinti Carlo Bertoldi The Impact of Nonsurgical Periodontal Therapy on the Salivary Proteome: A Pilot Study International Journal of Dentistry |
| title | The Impact of Nonsurgical Periodontal Therapy on the Salivary Proteome: A Pilot Study |
| title_full | The Impact of Nonsurgical Periodontal Therapy on the Salivary Proteome: A Pilot Study |
| title_fullStr | The Impact of Nonsurgical Periodontal Therapy on the Salivary Proteome: A Pilot Study |
| title_full_unstemmed | The Impact of Nonsurgical Periodontal Therapy on the Salivary Proteome: A Pilot Study |
| title_short | The Impact of Nonsurgical Periodontal Therapy on the Salivary Proteome: A Pilot Study |
| title_sort | impact of nonsurgical periodontal therapy on the salivary proteome a pilot study |
| url | http://dx.doi.org/10.1155/ijod/6655743 |
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