Reverse Submammary Adipofascial Perforator Flap: Preliminary Results of a Dual-plane, Acellular Dermal Matrix–free, Direct-to-implant Hybrid Reconstruction

Background:. Single-stage direct-to-implant (DTI) reconstruction, particularly the prepectoral technique, has become prominent due to its reliable outcomes and shorter operative time. This approach spares the pectoralis major muscle, reducing postoperative pain and morbidity, and ensuring quicker re...

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Main Authors: Diego Ribuffo, MD, PhD, Marco Marcasciano, MD, PhD, Federico Lo Torto, MD, PhD, Jacopo Nanni, MD, Luca Patanè, MD, Lorenzo Calabrese, MD, Davide Marino, MD, Donato Casella, MD, PhD, Manfredi Greco, MD, PhD
Format: Article
Language:English
Published: Wolters Kluwer 2025-06-01
Series:Plastic and Reconstructive Surgery, Global Open
Online Access:http://journals.lww.com/prsgo/fulltext/10.1097/GOX.0000000000006847
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author Diego Ribuffo, MD, PhD
Marco Marcasciano, MD, PhD
Federico Lo Torto, MD, PhD
Jacopo Nanni, MD
Luca Patanè, MD
Lorenzo Calabrese, MD
Davide Marino, MD
Donato Casella, MD, PhD
Manfredi Greco, MD, PhD
author_facet Diego Ribuffo, MD, PhD
Marco Marcasciano, MD, PhD
Federico Lo Torto, MD, PhD
Jacopo Nanni, MD
Luca Patanè, MD
Lorenzo Calabrese, MD
Davide Marino, MD
Donato Casella, MD, PhD
Manfredi Greco, MD, PhD
author_sort Diego Ribuffo, MD, PhD
collection DOAJ
description Background:. Single-stage direct-to-implant (DTI) reconstruction, particularly the prepectoral technique, has become prominent due to its reliable outcomes and shorter operative time. This approach spares the pectoralis major muscle, reducing postoperative pain and morbidity, and ensuring quicker recovery. However, limitations such as patient comorbidities and tumor characteristics can limit feasibility, leading to complications and high reconstructive failure rates. In such cases, switching to autologous or 2-stage approaches becomes necessary. This study introduced an innovative acellular dermal matrix–free dual-plane DTI hybrid reconstruction using a reverse submammary adipofascial perforator flap for small-volume breasts. Methods:. A prospective noncontrolled cohort study was conducted from January to April 2024, enrolling 10 breast cancer patients eligible for DTI reconstruction. Data collected included preoperative clinical characteristics, intraoperative surgical data, and postoperative outcomes, including complications and patient satisfaction measured using BREAST-Q version 2.0. Breast aesthetics was also evaluated by 12 independent observers at minimum 3 months follow-up. Results:. The surgical technique involved a dual-plane pocket with a reverse submammary adipofascial perforator flap, harvested from the inframammary fold, anchored to the pectoralis major muscle for inferolateral pole coverage of the breast implant. Results showed 1 major complication requiring surgical revision and 1 minor skin flap necrosis managed conservatively. All patients reported good satisfaction with their reconstruction results, supported by positive aesthetic evaluations from observers. Conclusions:. This acellular dermal matrix–free, dual-plane DTI hybrid technique seems safe and effective for small-volume breasts. It offers a viable alternative for selected cases, warranting further investigation with larger cohorts and longer follow-ups.
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spelling doaj-art-b3265d07d63c4ffa99864e31108a4ab72025-08-20T03:47:21ZengWolters KluwerPlastic and Reconstructive Surgery, Global Open2169-75742025-06-01136e684710.1097/GOX.0000000000006847202506000-00048Reverse Submammary Adipofascial Perforator Flap: Preliminary Results of a Dual-plane, Acellular Dermal Matrix–free, Direct-to-implant Hybrid ReconstructionDiego Ribuffo, MD, PhD0Marco Marcasciano, MD, PhD1Federico Lo Torto, MD, PhD2Jacopo Nanni, MD3Luca Patanè, MD4Lorenzo Calabrese, MD5Davide Marino, MD6Donato Casella, MD, PhD7Manfredi Greco, MD, PhD8From the * Department of Surgery “P. Valdoni,” Unit of Plastic and Reconstructive Surgery, "Sapienza" University of Rome, Policlinico Umberto I, Rome, Italy† Plastic and Reconstructive Surgery Unit, Department of Experimental and Clinical Medicine, “Magna Graecia” University of Catanzaro, AOU Renato Dulbecco, Catanzaro, ItalyFrom the * Department of Surgery “P. Valdoni,” Unit of Plastic and Reconstructive Surgery, "Sapienza" University of Rome, Policlinico Umberto I, Rome, Italy† Plastic and Reconstructive Surgery Unit, Department of Experimental and Clinical Medicine, “Magna Graecia” University of Catanzaro, AOU Renato Dulbecco, Catanzaro, ItalyFrom the * Department of Surgery “P. Valdoni,” Unit of Plastic and Reconstructive Surgery, "Sapienza" University of Rome, Policlinico Umberto I, Rome, ItalyFrom the * Department of Surgery “P. Valdoni,” Unit of Plastic and Reconstructive Surgery, "Sapienza" University of Rome, Policlinico Umberto I, Rome, ItalyFrom the * Department of Surgery “P. Valdoni,” Unit of Plastic and Reconstructive Surgery, "Sapienza" University of Rome, Policlinico Umberto I, Rome, Italy‡ Department of Breast Cancer Surgery, Azienda Ospedaliero-Universitaria Senese, Siena, Italy§ Department of Surgery “P. Valdoni", "Sapienza" University of Rome, Plastic and Reconstructive Surgery Unit, “Santa Maria Goretti” Hospital, Latina, Italy.Background:. Single-stage direct-to-implant (DTI) reconstruction, particularly the prepectoral technique, has become prominent due to its reliable outcomes and shorter operative time. This approach spares the pectoralis major muscle, reducing postoperative pain and morbidity, and ensuring quicker recovery. However, limitations such as patient comorbidities and tumor characteristics can limit feasibility, leading to complications and high reconstructive failure rates. In such cases, switching to autologous or 2-stage approaches becomes necessary. This study introduced an innovative acellular dermal matrix–free dual-plane DTI hybrid reconstruction using a reverse submammary adipofascial perforator flap for small-volume breasts. Methods:. A prospective noncontrolled cohort study was conducted from January to April 2024, enrolling 10 breast cancer patients eligible for DTI reconstruction. Data collected included preoperative clinical characteristics, intraoperative surgical data, and postoperative outcomes, including complications and patient satisfaction measured using BREAST-Q version 2.0. Breast aesthetics was also evaluated by 12 independent observers at minimum 3 months follow-up. Results:. The surgical technique involved a dual-plane pocket with a reverse submammary adipofascial perforator flap, harvested from the inframammary fold, anchored to the pectoralis major muscle for inferolateral pole coverage of the breast implant. Results showed 1 major complication requiring surgical revision and 1 minor skin flap necrosis managed conservatively. All patients reported good satisfaction with their reconstruction results, supported by positive aesthetic evaluations from observers. Conclusions:. This acellular dermal matrix–free, dual-plane DTI hybrid technique seems safe and effective for small-volume breasts. It offers a viable alternative for selected cases, warranting further investigation with larger cohorts and longer follow-ups.http://journals.lww.com/prsgo/fulltext/10.1097/GOX.0000000000006847
spellingShingle Diego Ribuffo, MD, PhD
Marco Marcasciano, MD, PhD
Federico Lo Torto, MD, PhD
Jacopo Nanni, MD
Luca Patanè, MD
Lorenzo Calabrese, MD
Davide Marino, MD
Donato Casella, MD, PhD
Manfredi Greco, MD, PhD
Reverse Submammary Adipofascial Perforator Flap: Preliminary Results of a Dual-plane, Acellular Dermal Matrix–free, Direct-to-implant Hybrid Reconstruction
Plastic and Reconstructive Surgery, Global Open
title Reverse Submammary Adipofascial Perforator Flap: Preliminary Results of a Dual-plane, Acellular Dermal Matrix–free, Direct-to-implant Hybrid Reconstruction
title_full Reverse Submammary Adipofascial Perforator Flap: Preliminary Results of a Dual-plane, Acellular Dermal Matrix–free, Direct-to-implant Hybrid Reconstruction
title_fullStr Reverse Submammary Adipofascial Perforator Flap: Preliminary Results of a Dual-plane, Acellular Dermal Matrix–free, Direct-to-implant Hybrid Reconstruction
title_full_unstemmed Reverse Submammary Adipofascial Perforator Flap: Preliminary Results of a Dual-plane, Acellular Dermal Matrix–free, Direct-to-implant Hybrid Reconstruction
title_short Reverse Submammary Adipofascial Perforator Flap: Preliminary Results of a Dual-plane, Acellular Dermal Matrix–free, Direct-to-implant Hybrid Reconstruction
title_sort reverse submammary adipofascial perforator flap preliminary results of a dual plane acellular dermal matrix free direct to implant hybrid reconstruction
url http://journals.lww.com/prsgo/fulltext/10.1097/GOX.0000000000006847
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