Transcription factor GATA4 associates with mesenchymal-like gene expression in human hepatoblastoma cells
GATA4, a transcription factor crucial for early liver development, has been implicated in the pathophysiology of hepatoblastoma, an embryonal tumor of childhood. However, the molecular and phenotypic consequences of GATA4 expression in hepatoblastoma are not fully understood. We surveyed GATA4 expre...
Saved in:
| Main Authors: | Tea Soini, Katja Eloranta, Marjut Pihlajoki, Antti Kyrönlahti, Oyediran Akinrinade, Noora Andersson, Jouko Lohi, Mikko P Pakarinen, David B Wilson, Markku Heikinheimo |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2018-08-01
|
| Series: | Tumor Biology |
| Online Access: | https://doi.org/10.1177/1010428318785498 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Downregulation of transcription factor GATA4 sensitizes human hepatoblastoma cells to doxorubicin-induced apoptosis
by: Tea Soini, et al.
Published: (2017-03-01) -
Functional screening identifies kinesin spindle protein inhibitor filanesib as a potential treatment option for hepatoblastoma
by: Ruth Nousiainen, et al.
Published: (2025-04-01) -
Insights into the mechanisms of angiogenesis in hepatoblastoma
by: Meng Kong, et al.
Published: (2025-05-01) -
The importance of age as a prognostic predictor of childhood hepatoblastoma: an analysis of single-center childhood hepatoblastoma in China
by: Zhen Li, et al.
Published: (2025-03-01) -
Hepatoblastoma: From Molecular Mechanisms to Therapeutic Strategies
by: Ling Fan, et al.
Published: (2025-03-01)