Anti-endothelial cell antibodies in pathogenesis of vasculitis

Anti-endothelial cell antibodies in pathogenesis of vasculitis

Vasculitis is a group of syndromes characterized by inflammation, presence of autoantibodies and endothelial cells (ECs) damage, which lead to stenosis or occlusion of the vascular lumen. Anti-endothelial cell antibodies (AECAs) are a heterogeneous group of autoantibodies in vasculitis. AECAs bind t...

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Bibliographic Details
Main Authors: Tian Zhang, Liqun Li, Shengshi Huang, Maria N. Starodubtseva, Ju Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Immunology
Subjects:
vasculitis
endothelial cells
anti-endothelial cell antibodies (AECAs)
angiogenesis
mechanical properties
stiffness
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1567293/full
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