The critical role of primary care clinicians in the early detection of ocular surface squamous neoplasia

Ocular surface squamous neoplasia (OSSN) encompasses a spectrum of conjunctival tumours and, while rare globally, is the most common ocular malignancy in sub-Saharan Africa. Its rising incidence, primarily driven by the human immunodeficiency virus (HIV) epidemic, presents significant challenges in...

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Main Authors: Leendert Dekker, Jan F. Olivier, Klaus von Pressentin
Format: Article
Language:English
Published: AOSIS 2025-02-01
Series:South African Family Practice
Subjects:
Online Access:https://safpj.co.za/index.php/safpj/article/view/6065
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author Leendert Dekker
Jan F. Olivier
Klaus von Pressentin
author_facet Leendert Dekker
Jan F. Olivier
Klaus von Pressentin
author_sort Leendert Dekker
collection DOAJ
description Ocular surface squamous neoplasia (OSSN) encompasses a spectrum of conjunctival tumours and, while rare globally, is the most common ocular malignancy in sub-Saharan Africa. Its rising incidence, primarily driven by the human immunodeficiency virus (HIV) epidemic, presents significant challenges in clinical diagnosis, as these lesions often share characteristics with other conjunctival lesions. In South Africa, where risk factors such as HIV, human papillomavirus infection and excessive sun exposure are prevalent, primary care clinicians play a crucial role in identifying and referring cases for early intervention. Ocular surface squamous neoplasia is often the first indication of HIV in patients who are otherwise unaware of their status when they present to healthcare workers, making it essential for healthcare workers to screen for HIV and initiate antiretroviral therapy. Early recognition of at-risk patients and prompt referral of suspicious lesions are imperative to improve patient outcomes and prevent vision loss.
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institution Kabale University
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language English
publishDate 2025-02-01
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series South African Family Practice
spelling doaj-art-b30c70616dc640d6afdcb7ea6f2964d12025-02-11T13:26:42ZengAOSISSouth African Family Practice2078-61902078-62042025-02-01671e1e510.4102/safp.v67i1.60654907The critical role of primary care clinicians in the early detection of ocular surface squamous neoplasiaLeendert Dekker0Jan F. Olivier1Klaus von Pressentin2Department of Ophthalmology, Faculty of Medicine, Dr George Mukhari Academic Hospital, City of TshwaneDepartment of Ophthalmology, Faculty of Medicine, Sefako Makgatho Health Sciences University, City of TshwaneDivision of Family Medicine, Department of Family, Community and Emergency Care, Faculty of Health Sciences, University of Cape Town, Cape TownOcular surface squamous neoplasia (OSSN) encompasses a spectrum of conjunctival tumours and, while rare globally, is the most common ocular malignancy in sub-Saharan Africa. Its rising incidence, primarily driven by the human immunodeficiency virus (HIV) epidemic, presents significant challenges in clinical diagnosis, as these lesions often share characteristics with other conjunctival lesions. In South Africa, where risk factors such as HIV, human papillomavirus infection and excessive sun exposure are prevalent, primary care clinicians play a crucial role in identifying and referring cases for early intervention. Ocular surface squamous neoplasia is often the first indication of HIV in patients who are otherwise unaware of their status when they present to healthcare workers, making it essential for healthcare workers to screen for HIV and initiate antiretroviral therapy. Early recognition of at-risk patients and prompt referral of suspicious lesions are imperative to improve patient outcomes and prevent vision loss.https://safpj.co.za/index.php/safpj/article/view/6065ocular surface squamous neoplasiaossnhpvhivultraviolet radiationprimary care.
spellingShingle Leendert Dekker
Jan F. Olivier
Klaus von Pressentin
The critical role of primary care clinicians in the early detection of ocular surface squamous neoplasia
South African Family Practice
ocular surface squamous neoplasia
ossn
hpv
hiv
ultraviolet radiation
primary care.
title The critical role of primary care clinicians in the early detection of ocular surface squamous neoplasia
title_full The critical role of primary care clinicians in the early detection of ocular surface squamous neoplasia
title_fullStr The critical role of primary care clinicians in the early detection of ocular surface squamous neoplasia
title_full_unstemmed The critical role of primary care clinicians in the early detection of ocular surface squamous neoplasia
title_short The critical role of primary care clinicians in the early detection of ocular surface squamous neoplasia
title_sort critical role of primary care clinicians in the early detection of ocular surface squamous neoplasia
topic ocular surface squamous neoplasia
ossn
hpv
hiv
ultraviolet radiation
primary care.
url https://safpj.co.za/index.php/safpj/article/view/6065
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