Protocol for modeling blood flow recovery and angiogenesis in response to hindlimb ischemia

Protocol for modeling blood flow recovery and angiogenesis in response to hindlimb ischemia

Summary: Here, we present a protocol that models peripheral artery disease using the surgical induction of hindlimb ischemia (HLI) in mice. We list the steps to surgically excise the femoral artery and assess blood flow recovery through laser Doppler imaging. We then detail procedures for visualizin...

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Bibliographic Details
Main Authors: Sheila Sharma, Julia Pierce, Celia A. Butler, Olivya Caballero, Chris Mantsounga, Alan R. Morrison
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:STAR Protocols
Subjects:
Health Sciences
Immunology
Microscopy
Model Organisms
Molecular Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2666166725001893
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