Measles seroprevalence in Thailand: are adolescents and young adults at risk of measles?
Introduction: During the last decade, measles has become an important re-emerging disease in Thailand. The objective of this study was to measure measles seroprevalence and its influencing factors so as to plan an improved vaccination programme. Methods: A total of 600 participants aged between 9 mo...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer – Medknow Publications
2024-06-01
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| Series: | Singapore Medical Journal |
| Subjects: | |
| Online Access: | https://journals.lww.com/10.11622/smedj.2022058 |
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| Summary: | Introduction:
During the last decade, measles has become an important re-emerging disease in Thailand. The objective of this study was to measure measles seroprevalence and its influencing factors so as to plan an improved vaccination programme.
Methods:
A total of 600 participants aged between 9 months and 50 years were divided into seven groups representing birth cohorts that experienced different measles vaccination policies. Participants’ blood samples were obtained to measure measles immunoglobulin G (IgG) levels.
Results:
None of the participants in the age group of 9 months had measles IgG levels beyond a protective level. Participants in the age groups 2.5, 5–15, 16–29, 30–33, 34–40 and 41–50 years had 82% (95% confidence interval [CI] 73.3–90.7), 50% (95% CI 36.1–63.9), 52% (95% CI 42.3–62.7), 70% (95% CI 61.1–78.9), 88.8% (95% CI 84.1–93.5) and 98.8% (95% CI 96.4–100.0) measles seropositivity, respectively. The study did not find any significant factors affecting measles seropositivity.
Conclusion:
Individuals aged 15–34 years are vulnerable to measles infections. Supplementary vaccination should be encouraged in special situations, including postexposure prophylaxis for young adults during an outbreak and for high-risk occupations such as healthcare personnel. |
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| ISSN: | 0037-5675 2737-5935 |