Identification of immune-related biomarkers linked to systemic lupus erythematosus and dilated cardiomyopathy through integrated bioinformatics analysis and multiple machine learning algorithms

Identification of immune-related biomarkers linked to systemic lupus erythematosus and dilated cardiomyopathy through integrated bioinformatics analysis and multiple machine learning algorithms

BackgroundEpidemiological evidence indicates that up to 50% of systemic lupus erythematosus (SLE) patients exhibit cardiac involvement, suggesting a potential strong association between SLE and dilated cardiomyopathy (DCM). This study aims to identify SLE-related genes that may contribute to DCM dev...

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Bibliographic Details
Main Authors: Gaijie Li, Liwen Lin, Shushu Wang, Kachun Lu, KaMan Szeto, Guiting Zhou, Xianwen Tang, Chuanjin Luo
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Immunology
Subjects:
systemic lupus erythematosus
immune cell infiltration
diagnostic model
bioinformatics analysis
dilated cardiomyopathy
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1606920/full
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