Suspected Pericardial Tuberculosis Revealed as an Amyloid Pericardial Mass
Primary systemic amyloidosis is not easily diagnosed. The immunoglobulin deposits are usually localized in the kidney, heart, and liver. We describe an unusual case of a patient suffering from a pericardial amyloidoma with internal calcifications and air bubbles that compressed the right ventricle a...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | Case Reports in Hematology |
| Online Access: | http://dx.doi.org/10.1155/2018/8606430 |
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| author | Sebastiano Cicco Antonio G. Solimando Patrizia Leone Stefano Battaglia Roberto Ria Angelo Vacca Vito Racanelli |
| author_facet | Sebastiano Cicco Antonio G. Solimando Patrizia Leone Stefano Battaglia Roberto Ria Angelo Vacca Vito Racanelli |
| author_sort | Sebastiano Cicco |
| collection | DOAJ |
| description | Primary systemic amyloidosis is not easily diagnosed. The immunoglobulin deposits are usually localized in the kidney, heart, and liver. We describe an unusual case of a patient suffering from a pericardial amyloidoma with internal calcifications and air bubbles that compressed the right ventricle and shifted the heart to the left. Since the patient was in shock, urgent pericardiotomy was performed. This site showed PET uptake. A monoclonal component was present. On these findings, differential diagnoses included multiple myeloma and atypical pericardial tuberculosis, whereas a periumbilical fat tissue biopsy demonstrated amyloidosis. A previous Salmonella species infection had most likely stimulated the production of amyloid. The patient received bortezomib/dexamethasone treatment and achieved a good response. |
| format | Article |
| id | doaj-art-b300681b59b0436fb932003c17132dc5 |
| institution | Kabale University |
| issn | 2090-6560 2090-6579 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Hematology |
| spelling | doaj-art-b300681b59b0436fb932003c17132dc52025-02-03T01:11:01ZengWileyCase Reports in Hematology2090-65602090-65792018-01-01201810.1155/2018/86064308606430Suspected Pericardial Tuberculosis Revealed as an Amyloid Pericardial MassSebastiano Cicco0Antonio G. Solimando1Patrizia Leone2Stefano Battaglia3Roberto Ria4Angelo Vacca5Vito Racanelli6Department of Biomedical Sciences and Human Oncology, Section of Internal Medicine “G. Baccelli”, University of Bari Aldo Moro Medical School, Bari, ItalyDepartment of Biomedical Sciences and Human Oncology, Section of Internal Medicine “G. Baccelli”, University of Bari Aldo Moro Medical School, Bari, ItalyDepartment of Biomedical Sciences and Human Oncology, Section of Internal Medicine “G. Baccelli”, University of Bari Aldo Moro Medical School, Bari, ItalyDepartment of Biomedical Sciences and Human Oncology, Section of Internal Medicine “G. Baccelli”, University of Bari Aldo Moro Medical School, Bari, ItalyDepartment of Biomedical Sciences and Human Oncology, Section of Internal Medicine “G. Baccelli”, University of Bari Aldo Moro Medical School, Bari, ItalyDepartment of Biomedical Sciences and Human Oncology, Section of Internal Medicine “G. Baccelli”, University of Bari Aldo Moro Medical School, Bari, ItalyDepartment of Biomedical Sciences and Human Oncology, Section of Internal Medicine “G. Baccelli”, University of Bari Aldo Moro Medical School, Bari, ItalyPrimary systemic amyloidosis is not easily diagnosed. The immunoglobulin deposits are usually localized in the kidney, heart, and liver. We describe an unusual case of a patient suffering from a pericardial amyloidoma with internal calcifications and air bubbles that compressed the right ventricle and shifted the heart to the left. Since the patient was in shock, urgent pericardiotomy was performed. This site showed PET uptake. A monoclonal component was present. On these findings, differential diagnoses included multiple myeloma and atypical pericardial tuberculosis, whereas a periumbilical fat tissue biopsy demonstrated amyloidosis. A previous Salmonella species infection had most likely stimulated the production of amyloid. The patient received bortezomib/dexamethasone treatment and achieved a good response.http://dx.doi.org/10.1155/2018/8606430 |
| spellingShingle | Sebastiano Cicco Antonio G. Solimando Patrizia Leone Stefano Battaglia Roberto Ria Angelo Vacca Vito Racanelli Suspected Pericardial Tuberculosis Revealed as an Amyloid Pericardial Mass Case Reports in Hematology |
| title | Suspected Pericardial Tuberculosis Revealed as an Amyloid Pericardial Mass |
| title_full | Suspected Pericardial Tuberculosis Revealed as an Amyloid Pericardial Mass |
| title_fullStr | Suspected Pericardial Tuberculosis Revealed as an Amyloid Pericardial Mass |
| title_full_unstemmed | Suspected Pericardial Tuberculosis Revealed as an Amyloid Pericardial Mass |
| title_short | Suspected Pericardial Tuberculosis Revealed as an Amyloid Pericardial Mass |
| title_sort | suspected pericardial tuberculosis revealed as an amyloid pericardial mass |
| url | http://dx.doi.org/10.1155/2018/8606430 |
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