Amlodipine-Induced Gingival Hyperplasia in a Young Male with Stage 5 Chronic Kidney Disease

Gingival hyperplasia is a rare finding in clinical practice. Nevertheless, when it occurs, it is a finding of great value as it can lead to definite clinical diagnosis. The present case is a 19-year-old male who was referred for further management of stage 5 chronic kidney disease. On evaluation, he...

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Main Authors: Kevin John, Ajay Kumar Mishra, Karthik Gunasekaran, Ramya Iyyadurai
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Case Reports in Nephrology
Online Access:http://dx.doi.org/10.1155/2020/7801546
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author Kevin John
Ajay Kumar Mishra
Karthik Gunasekaran
Ramya Iyyadurai
author_facet Kevin John
Ajay Kumar Mishra
Karthik Gunasekaran
Ramya Iyyadurai
author_sort Kevin John
collection DOAJ
description Gingival hyperplasia is a rare finding in clinical practice. Nevertheless, when it occurs, it is a finding of great value as it can lead to definite clinical diagnosis. The present case is a 19-year-old male who was referred for further management of stage 5 chronic kidney disease. On evaluation, he was found to have gingival hyperplasia. He was evaluated for reversible causes of kidney disease, and since none were found, renal replacement therapy was advised. He had been taking amlodipine for blood pressure control. As this was presumed to be the cause of gingival hyperplasia, it was stopped and replaced by a combination of beta-blocker and prazosin. At six-month follow-up, he had complete resolution of gingival hyperplasia. Amlodipine as a cause of gingival hyperplasia is a rare occurrence. However, it is crucial to keep in mind such a possible side effect of this commonly prescribed antihypertensive drug.
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series Case Reports in Nephrology
spelling doaj-art-b2fd4e00c6b045e694dda73c9b0cb8df2025-08-20T03:39:21ZengWileyCase Reports in Nephrology2090-66412090-665X2020-01-01202010.1155/2020/78015467801546Amlodipine-Induced Gingival Hyperplasia in a Young Male with Stage 5 Chronic Kidney DiseaseKevin John0Ajay Kumar Mishra1Karthik Gunasekaran2Ramya Iyyadurai3Department of Medicine, Christian Medical College, Vellore, IndiaDepartment of Medicine, Christian Medical College, Vellore, IndiaDepartment of Medicine, Christian Medical College, Vellore, IndiaDepartment of Medicine, Christian Medical College, Vellore, IndiaGingival hyperplasia is a rare finding in clinical practice. Nevertheless, when it occurs, it is a finding of great value as it can lead to definite clinical diagnosis. The present case is a 19-year-old male who was referred for further management of stage 5 chronic kidney disease. On evaluation, he was found to have gingival hyperplasia. He was evaluated for reversible causes of kidney disease, and since none were found, renal replacement therapy was advised. He had been taking amlodipine for blood pressure control. As this was presumed to be the cause of gingival hyperplasia, it was stopped and replaced by a combination of beta-blocker and prazosin. At six-month follow-up, he had complete resolution of gingival hyperplasia. Amlodipine as a cause of gingival hyperplasia is a rare occurrence. However, it is crucial to keep in mind such a possible side effect of this commonly prescribed antihypertensive drug.http://dx.doi.org/10.1155/2020/7801546
spellingShingle Kevin John
Ajay Kumar Mishra
Karthik Gunasekaran
Ramya Iyyadurai
Amlodipine-Induced Gingival Hyperplasia in a Young Male with Stage 5 Chronic Kidney Disease
Case Reports in Nephrology
title Amlodipine-Induced Gingival Hyperplasia in a Young Male with Stage 5 Chronic Kidney Disease
title_full Amlodipine-Induced Gingival Hyperplasia in a Young Male with Stage 5 Chronic Kidney Disease
title_fullStr Amlodipine-Induced Gingival Hyperplasia in a Young Male with Stage 5 Chronic Kidney Disease
title_full_unstemmed Amlodipine-Induced Gingival Hyperplasia in a Young Male with Stage 5 Chronic Kidney Disease
title_short Amlodipine-Induced Gingival Hyperplasia in a Young Male with Stage 5 Chronic Kidney Disease
title_sort amlodipine induced gingival hyperplasia in a young male with stage 5 chronic kidney disease
url http://dx.doi.org/10.1155/2020/7801546
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AT karthikgunasekaran amlodipineinducedgingivalhyperplasiainayoungmalewithstage5chronickidneydisease
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