THE PATHOGENESIS OF IRON DEFICIENCY ANEMIA IN OBESITY
Iron deficiency anemia and obesity have become a global problem affecting not only high income countries but also developing countries. Experimental and clinical studies indicate that there is a relationship between iron metabolism and weight status. Obesity is associated with low-grade systemic inf...
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| Format: | Article |
| Language: | English |
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Poltava State Medical University
2017-03-01
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| Series: | Проблеми екології та медицини |
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| Online Access: | https://ecomed-journal.org/index.php/journal/article/view/16 |
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| author | V.M. Nedoborenko I.P. Kaidashev |
| author_facet | V.M. Nedoborenko I.P. Kaidashev |
| author_sort | V.M. Nedoborenko |
| collection | DOAJ |
| description | Iron deficiency anemia and obesity have become a global problem affecting not only high income countries but also developing countries. Experimental and clinical studies indicate that there is a relationship between iron metabolism and weight status. Obesity is associated with low-grade systemic inflammation and elevated hepcidin concentrations. Hepcidin is the key regulator of systemic iron homeostasis. This review summarizes the current understanding of the dysregulation of iron homeostasis in obesity and leads assumptions about treatment. |
| format | Article |
| id | doaj-art-b2fcb2d8093e4b03acae669ecaa92738 |
| institution | Kabale University |
| issn | 2073-4662 2519-2302 |
| language | English |
| publishDate | 2017-03-01 |
| publisher | Poltava State Medical University |
| record_format | Article |
| series | Проблеми екології та медицини |
| spelling | doaj-art-b2fcb2d8093e4b03acae669ecaa927382025-08-20T03:39:21ZengPoltava State Medical UniversityПроблеми екології та медицини2073-46622519-23022017-03-01203-4131516THE PATHOGENESIS OF IRON DEFICIENCY ANEMIA IN OBESITYV.M. Nedoborenko0I.P. Kaidashev1Higher State Educational Establishment of Ukraine "Ukrainian Medical Stomatological Academy"Higher State Educational Establishment of Ukraine "Ukrainian Medical Stomatological Academy"Iron deficiency anemia and obesity have become a global problem affecting not only high income countries but also developing countries. Experimental and clinical studies indicate that there is a relationship between iron metabolism and weight status. Obesity is associated with low-grade systemic inflammation and elevated hepcidin concentrations. Hepcidin is the key regulator of systemic iron homeostasis. This review summarizes the current understanding of the dysregulation of iron homeostasis in obesity and leads assumptions about treatment.https://ecomed-journal.org/index.php/journal/article/view/16obesity, low-grade systemic inflammation, hepcidin, iron deficiency anemia |
| spellingShingle | V.M. Nedoborenko I.P. Kaidashev THE PATHOGENESIS OF IRON DEFICIENCY ANEMIA IN OBESITY Проблеми екології та медицини obesity, low-grade systemic inflammation, hepcidin, iron deficiency anemia |
| title | THE PATHOGENESIS OF IRON DEFICIENCY ANEMIA IN OBESITY |
| title_full | THE PATHOGENESIS OF IRON DEFICIENCY ANEMIA IN OBESITY |
| title_fullStr | THE PATHOGENESIS OF IRON DEFICIENCY ANEMIA IN OBESITY |
| title_full_unstemmed | THE PATHOGENESIS OF IRON DEFICIENCY ANEMIA IN OBESITY |
| title_short | THE PATHOGENESIS OF IRON DEFICIENCY ANEMIA IN OBESITY |
| title_sort | pathogenesis of iron deficiency anemia in obesity |
| topic | obesity, low-grade systemic inflammation, hepcidin, iron deficiency anemia |
| url | https://ecomed-journal.org/index.php/journal/article/view/16 |
| work_keys_str_mv | AT vmnedoborenko thepathogenesisofirondeficiencyanemiainobesity AT ipkaidashev thepathogenesisofirondeficiencyanemiainobesity AT vmnedoborenko pathogenesisofirondeficiencyanemiainobesity AT ipkaidashev pathogenesisofirondeficiencyanemiainobesity |