High rheumatoid factor does not diminish efficacy of TNF inhibitors in seropositive JIA

High rheumatoid factor does not diminish efficacy of TNF inhibitors in seropositive JIA

Abstract Objectives Rheumatoid factor (RF) binds to the immunoglobulin Fc portion, which might influence the efficacy of Fc-carrying TNF inhibitors (TNFi). This has been shown in studies in adults with RF-positive RA, but not yet in children. The aim of this study was to determine efficacy of TNFi i...

Full description

Saved in:
Bibliographic Details
Main Authors: Boris Hügle, Gerd Horneff, Johannes-Peter Haas
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Pediatric Rheumatology Online Journal
Subjects:
Juvenile idiopathic arthritis
Rheumatoid factor
TNF inhibitor
Online Access:https://doi.org/10.1186/s12969-025-01125-z
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items