Targeting Death Receptor 5 (DR5) for the imaging and treatment of primary bone and soft tissue tumors: an update of the literature

Targeting Death Receptor 5 (DR5) for the imaging and treatment of primary bone and soft tissue tumors: an update of the literature

BackgroundDeath Receptor 5 (DR5) is expressed on the surface of primary bone and soft tissue sarcoma cells, and its activation induces cell death primarily through apoptosis. The combination of DR5 agonists and commonly used chemotherapeutic agents, such as doxorubicin, can promote cell death. Curre...

Full description

Saved in:
Bibliographic Details
Main Authors: Zakareya Gamie, Anja Krippner-Heidenreich, Craig Gerrand, Kenneth Samora Rankin
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-09-01
Series:Frontiers in Molecular Biosciences
Subjects:
death
receptor
TRAIL
agonist
imaging
apoptosis
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2024.1384795/full
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items