Non‐exposed endoscopic wall‐inversion surgery for an early gastric cancer arising from heterotopic submucosal gastric glands: A case report

Abstract A 74‐year‐old man, who was scheduled for surgery against the main duct‐type intraductal papillary mucinous neoplasm of the pancreas, was found to have a subepithelial lesion of the stomach under esophagogastroduodenoscopy. Endoscopic ultrasound‐guided fine needle aspiration for the gastric...

Full description

Saved in:
Bibliographic Details
Main Authors: Takeshi Abe, Yosuke Toya, Kyohei Sugai, Mizuki Komai, Shunichi Yanai, Haruka Nikai, Shigeaki Baba, Ryo Sugimoto, Naoki Yanagawa, Takayuki Matsumoto
Format: Article
Language:English
Published: Wiley 2025-04-01
Series:DEN Open
Subjects:
Online Access:https://doi.org/10.1002/deo2.70097
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849714754789048320
author Takeshi Abe
Yosuke Toya
Kyohei Sugai
Mizuki Komai
Shunichi Yanai
Haruka Nikai
Shigeaki Baba
Ryo Sugimoto
Naoki Yanagawa
Takayuki Matsumoto
author_facet Takeshi Abe
Yosuke Toya
Kyohei Sugai
Mizuki Komai
Shunichi Yanai
Haruka Nikai
Shigeaki Baba
Ryo Sugimoto
Naoki Yanagawa
Takayuki Matsumoto
author_sort Takeshi Abe
collection DOAJ
description Abstract A 74‐year‐old man, who was scheduled for surgery against the main duct‐type intraductal papillary mucinous neoplasm of the pancreas, was found to have a subepithelial lesion of the stomach under esophagogastroduodenoscopy. Endoscopic ultrasound‐guided fine needle aspiration for the gastric lesion revealed adenocarcinoma cells. We thus considered carcinomas arising from heterotopic submucosal gastric glands and metastases from the pancreatic lesion as differential diagnoses. We first non‐exposed endoscopic wall‐inversion surgery to the lesion as a total biopsy. The gastric lesion was diagnosed as early gastric cancer originating from heterotopic submucosal gastric glands. The patient subsequently underwent a pylorus‐preserving pancreatoduodenectomy for the intraductal papillary mucinous neoplasm. Our experience suggests non‐exposed endoscopic wall‐inversion surgery is a useful and minimally invasive option for the diagnosis and treatment of gastric submucosal lesions, which are presumed to be malignant in nature.
format Article
id doaj-art-b2e87221bb3b42d1a75efcbca6ddccbb
institution DOAJ
issn 2692-4609
language English
publishDate 2025-04-01
publisher Wiley
record_format Article
series DEN Open
spelling doaj-art-b2e87221bb3b42d1a75efcbca6ddccbb2025-08-20T03:13:36ZengWileyDEN Open2692-46092025-04-0151n/an/a10.1002/deo2.70097Non‐exposed endoscopic wall‐inversion surgery for an early gastric cancer arising from heterotopic submucosal gastric glands: A case reportTakeshi Abe0Yosuke Toya1Kyohei Sugai2Mizuki Komai3Shunichi Yanai4Haruka Nikai5Shigeaki Baba6Ryo Sugimoto7Naoki Yanagawa8Takayuki Matsumoto9Division of Gastroenterology and Hepatology Department of Internal Medicine School of Medicine Iwate Medical University Iwate JapanDivision of Gastroenterology and Hepatology Department of Internal Medicine School of Medicine Iwate Medical University Iwate JapanDivision of Gastroenterology and Hepatology Department of Internal Medicine School of Medicine Iwate Medical University Iwate JapanDivision of Gastroenterology and Hepatology Department of Internal Medicine School of Medicine Iwate Medical University Iwate JapanDivision of Gastroenterology and Hepatology Department of Internal Medicine School of Medicine Iwate Medical University Iwate JapanDepartment of Surgery School of Medicine Iwate Medical University Iwate JapanDepartment of Surgery School of Medicine Iwate Medical University Iwate JapanDepartment of Molecular Diagnostic Pathology School of Medicine Iwate Medical University Iwate JapanDepartment of Molecular Diagnostic Pathology School of Medicine Iwate Medical University Iwate JapanDivision of Gastroenterology and Hepatology Department of Internal Medicine School of Medicine Iwate Medical University Iwate JapanAbstract A 74‐year‐old man, who was scheduled for surgery against the main duct‐type intraductal papillary mucinous neoplasm of the pancreas, was found to have a subepithelial lesion of the stomach under esophagogastroduodenoscopy. Endoscopic ultrasound‐guided fine needle aspiration for the gastric lesion revealed adenocarcinoma cells. We thus considered carcinomas arising from heterotopic submucosal gastric glands and metastases from the pancreatic lesion as differential diagnoses. We first non‐exposed endoscopic wall‐inversion surgery to the lesion as a total biopsy. The gastric lesion was diagnosed as early gastric cancer originating from heterotopic submucosal gastric glands. The patient subsequently underwent a pylorus‐preserving pancreatoduodenectomy for the intraductal papillary mucinous neoplasm. Our experience suggests non‐exposed endoscopic wall‐inversion surgery is a useful and minimally invasive option for the diagnosis and treatment of gastric submucosal lesions, which are presumed to be malignant in nature.https://doi.org/10.1002/deo2.70097early gastric cancerheterotopic submucosal gastric glandslaparoscopic and endoscopic cooperative surgerynon‐exposed endoscopic wall‐inversion surgerysubepithelial lesion
spellingShingle Takeshi Abe
Yosuke Toya
Kyohei Sugai
Mizuki Komai
Shunichi Yanai
Haruka Nikai
Shigeaki Baba
Ryo Sugimoto
Naoki Yanagawa
Takayuki Matsumoto
Non‐exposed endoscopic wall‐inversion surgery for an early gastric cancer arising from heterotopic submucosal gastric glands: A case report
DEN Open
early gastric cancer
heterotopic submucosal gastric glands
laparoscopic and endoscopic cooperative surgery
non‐exposed endoscopic wall‐inversion surgery
subepithelial lesion
title Non‐exposed endoscopic wall‐inversion surgery for an early gastric cancer arising from heterotopic submucosal gastric glands: A case report
title_full Non‐exposed endoscopic wall‐inversion surgery for an early gastric cancer arising from heterotopic submucosal gastric glands: A case report
title_fullStr Non‐exposed endoscopic wall‐inversion surgery for an early gastric cancer arising from heterotopic submucosal gastric glands: A case report
title_full_unstemmed Non‐exposed endoscopic wall‐inversion surgery for an early gastric cancer arising from heterotopic submucosal gastric glands: A case report
title_short Non‐exposed endoscopic wall‐inversion surgery for an early gastric cancer arising from heterotopic submucosal gastric glands: A case report
title_sort non exposed endoscopic wall inversion surgery for an early gastric cancer arising from heterotopic submucosal gastric glands a case report
topic early gastric cancer
heterotopic submucosal gastric glands
laparoscopic and endoscopic cooperative surgery
non‐exposed endoscopic wall‐inversion surgery
subepithelial lesion
url https://doi.org/10.1002/deo2.70097
work_keys_str_mv AT takeshiabe nonexposedendoscopicwallinversionsurgeryforanearlygastriccancerarisingfromheterotopicsubmucosalgastricglandsacasereport
AT yosuketoya nonexposedendoscopicwallinversionsurgeryforanearlygastriccancerarisingfromheterotopicsubmucosalgastricglandsacasereport
AT kyoheisugai nonexposedendoscopicwallinversionsurgeryforanearlygastriccancerarisingfromheterotopicsubmucosalgastricglandsacasereport
AT mizukikomai nonexposedendoscopicwallinversionsurgeryforanearlygastriccancerarisingfromheterotopicsubmucosalgastricglandsacasereport
AT shunichiyanai nonexposedendoscopicwallinversionsurgeryforanearlygastriccancerarisingfromheterotopicsubmucosalgastricglandsacasereport
AT harukanikai nonexposedendoscopicwallinversionsurgeryforanearlygastriccancerarisingfromheterotopicsubmucosalgastricglandsacasereport
AT shigeakibaba nonexposedendoscopicwallinversionsurgeryforanearlygastriccancerarisingfromheterotopicsubmucosalgastricglandsacasereport
AT ryosugimoto nonexposedendoscopicwallinversionsurgeryforanearlygastriccancerarisingfromheterotopicsubmucosalgastricglandsacasereport
AT naokiyanagawa nonexposedendoscopicwallinversionsurgeryforanearlygastriccancerarisingfromheterotopicsubmucosalgastricglandsacasereport
AT takayukimatsumoto nonexposedendoscopicwallinversionsurgeryforanearlygastriccancerarisingfromheterotopicsubmucosalgastricglandsacasereport