Efficacy of Carraguard-based microbicides in vivo despite variable in vitro activity.

Efficacy of Carraguard-based microbicides in vivo despite variable in vitro activity.

Anti-HIV microbicides are being investigated in clinical trials and understanding how promising strategies work, coincident with demonstrating efficacy in vivo, is central to advancing new generation microbicides. We evaluated Carraguard and a new generation Carraguard-based formulation containing t...

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Bibliographic Details
Main Authors: Stuart G Turville, Meropi Aravantinou, Todd Miller, Jessica Kenney, Aaron Teitelbaum, Lieyu Hu, Anne Chudolij, Tom M Zydowsky, Michael Piatak, Julian W Bess, Jeffrey D Lifson, James Blanchard, Agegnehu Gettie, Melissa Robbiani
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-09-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0003162&type=printable
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