Experimental aerosol survival of SARS-CoV-2 in artificial saliva and tissue culture media at medium and high humidity
SARS-CoV-2, the causative agent of the COVID-19 pandemic, may be transmitted via airborne droplets or contact with surfaces onto which droplets have deposited. In this study, the ability of SARS-CoV-2 to survive in the dark, at two different relative humidity values and within artificial saliva, a c...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2020-01-01
|
| Series: | Emerging Microbes and Infections |
| Subjects: | |
| Online Access: | https://www.tandfonline.com/doi/10.1080/22221751.2020.1777906 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850150240166871040 |
|---|---|
| author | Sophie J. Smither Lin S. Eastaugh James S. Findlay Mark S. Lever |
| author_facet | Sophie J. Smither Lin S. Eastaugh James S. Findlay Mark S. Lever |
| author_sort | Sophie J. Smither |
| collection | DOAJ |
| description | SARS-CoV-2, the causative agent of the COVID-19 pandemic, may be transmitted via airborne droplets or contact with surfaces onto which droplets have deposited. In this study, the ability of SARS-CoV-2 to survive in the dark, at two different relative humidity values and within artificial saliva, a clinically relevant matrix, was investigated. SARS-CoV-2 was found to be stable, in the dark, in a dynamic small particle aerosol under the four experimental conditions we tested and viable virus could still be detected after 90 minutes. The decay rate and half-life was determined and decay rates ranged from 0.4 to 2.27 % per minute and the half lives ranged from 30 to 177 minutes for the different conditions. This information can be used for advice and modelling and potential mitigation strategies. |
| format | Article |
| id | doaj-art-b2ccaadc2d3b40898c22e6e0fcc8f65e |
| institution | OA Journals |
| issn | 2222-1751 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Emerging Microbes and Infections |
| spelling | doaj-art-b2ccaadc2d3b40898c22e6e0fcc8f65e2025-08-20T02:26:37ZengTaylor & Francis GroupEmerging Microbes and Infections2222-17512020-01-01911415141710.1080/22221751.2020.1777906Experimental aerosol survival of SARS-CoV-2 in artificial saliva and tissue culture media at medium and high humiditySophie J. Smither0Lin S. Eastaugh1James S. Findlay2Mark S. Lever3Chemical Biological and Radiological Division, Defence Science and Technology Laboratory (Dstl), Wiltshire, UKChemical Biological and Radiological Division, Defence Science and Technology Laboratory (Dstl), Wiltshire, UKChemical Biological and Radiological Division, Defence Science and Technology Laboratory (Dstl), Wiltshire, UKChemical Biological and Radiological Division, Defence Science and Technology Laboratory (Dstl), Wiltshire, UKSARS-CoV-2, the causative agent of the COVID-19 pandemic, may be transmitted via airborne droplets or contact with surfaces onto which droplets have deposited. In this study, the ability of SARS-CoV-2 to survive in the dark, at two different relative humidity values and within artificial saliva, a clinically relevant matrix, was investigated. SARS-CoV-2 was found to be stable, in the dark, in a dynamic small particle aerosol under the four experimental conditions we tested and viable virus could still be detected after 90 minutes. The decay rate and half-life was determined and decay rates ranged from 0.4 to 2.27 % per minute and the half lives ranged from 30 to 177 minutes for the different conditions. This information can be used for advice and modelling and potential mitigation strategies.https://www.tandfonline.com/doi/10.1080/22221751.2020.1777906SARS-CoV-2coronavirussurvivalaerosolsalivahumidity |
| spellingShingle | Sophie J. Smither Lin S. Eastaugh James S. Findlay Mark S. Lever Experimental aerosol survival of SARS-CoV-2 in artificial saliva and tissue culture media at medium and high humidity Emerging Microbes and Infections SARS-CoV-2 coronavirus survival aerosol saliva humidity |
| title | Experimental aerosol survival of SARS-CoV-2 in artificial saliva and tissue culture media at medium and high humidity |
| title_full | Experimental aerosol survival of SARS-CoV-2 in artificial saliva and tissue culture media at medium and high humidity |
| title_fullStr | Experimental aerosol survival of SARS-CoV-2 in artificial saliva and tissue culture media at medium and high humidity |
| title_full_unstemmed | Experimental aerosol survival of SARS-CoV-2 in artificial saliva and tissue culture media at medium and high humidity |
| title_short | Experimental aerosol survival of SARS-CoV-2 in artificial saliva and tissue culture media at medium and high humidity |
| title_sort | experimental aerosol survival of sars cov 2 in artificial saliva and tissue culture media at medium and high humidity |
| topic | SARS-CoV-2 coronavirus survival aerosol saliva humidity |
| url | https://www.tandfonline.com/doi/10.1080/22221751.2020.1777906 |
| work_keys_str_mv | AT sophiejsmither experimentalaerosolsurvivalofsarscov2inartificialsalivaandtissueculturemediaatmediumandhighhumidity AT linseastaugh experimentalaerosolsurvivalofsarscov2inartificialsalivaandtissueculturemediaatmediumandhighhumidity AT jamessfindlay experimentalaerosolsurvivalofsarscov2inartificialsalivaandtissueculturemediaatmediumandhighhumidity AT markslever experimentalaerosolsurvivalofsarscov2inartificialsalivaandtissueculturemediaatmediumandhighhumidity |