Editorial: Enhancing T cell function: innovations in cancer immunotherapy

Editorial: Enhancing T cell function: innovations in cancer immunotherapy

Saved in:

Bibliographic Details
Main Authors:	Ji Zhang, Qihao Zhao, Qian Sun, Hong Jiang, Valentyn Oksenych, Xuefeng Wang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-05-01
Series:	Frontiers in Immunology
Subjects:	editorial: enhancing t cell function: innovations in cancer immunotherapy cancer immunotherapy CD8 + T cells stem-like CD8 + T cells car-t enhancing T cell function
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1615030/full
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Systematic exploration of the molecular characteristics of CD8+ T cells to predict the response to immunotherapy and the prognosis of patients with colon adenocarcinoma
by: Xin Shen, et al.
Published: (2024-12-01)

Tumor-infiltrating lymphocytes in NSCLC: from immune surveillance to immunotherapy
by: Haiyi Xue, et al.
Published: (2025-07-01)

CD161+CD127+CD8+ T cell subsets can predict the efficacy of anti-PD-1 immunotherapy in non-small cell lung cancer with diabetes mellitus
by: Jingjing Qu, et al.
Published: (2024-12-01)

Anti-TIGIT therapies: a review of preclinical and clinical efficacy and mechanisms
by: Erin C. Sundstrom, et al.
Published: (2025-07-01)

CD8+ T cell exhaustion in the tumor microenvironment of breast cancer
by: Hanghang Xie, et al.
Published: (2024-12-01)

The role of mitochondrial transfer in the suppression of CD8+ T cell responses by Mesenchymal stem cells
by: Loic Vaillant, et al.
Published: (2024-11-01)

Dual CD47 and PD‐L1 blockade elicits anti‐tumor immunity by intratumoral CD8+ T cells
by: Susan N Christo, et al.
Published: (2024-01-01)

Siglec‐G Suppresses CD8+ T Cells Responses through Metabolic Rewiring and Can be Targeted to Enhance Tumor Immunotherapy
by: Shenhui Yin, et al.
Published: (2024-12-01)

Salmonella immunotherapy engineered with highly efficient tumor antigen coating establishes antigen-specific CD8+ T cell immunity and increases in antitumor efficacy with type I interferon combination therapy
by: Suyang Wang, et al.
Published: (2024-12-01)

Metabolic alterations driven by LDHA in CD8 + T cells promote immune evasion and therapy resistance in NSCLC
by: Hao Wen, et al.
Published: (2025-07-01)

Anti-Tumor Efficacy of a Mesothelin-Based Nanovaccine in a KPC Orthotopic Mouse Model of Pancreatic Cancer
by: Daniele P. Ferrari, et al.
Published: (2025-03-01)

New insights on anti-tumor immunity of CD8+ T cells: cancer stem cells, tumor immune microenvironment and immunotherapy
by: Yibin Lin, et al.
Published: (2025-03-01)

Targeting tumor metabolism to augment CD8+ T cell anti-tumor immunity
by: Huan Liu, et al.
Published: (2025-05-01)

Interleukin-27 tackles immunosuppression in chronic lymphocytic leukemia
by: Iria Fernandez Botana, et al.
Published: (2023-12-01)

CAR-iNKT cells: redefining the frontiers of cellular immunotherapy
by: Magdalena Niedzielska, et al.
Published: (2025-07-01)

Intrinsic STING of CD8 + T cells regulates self-metabolic reprogramming and memory to exert anti-tumor effects
by: Qiuli Xu, et al.
Published: (2025-02-01)

CD73+CD8+ T cells define a subset with anti-tumor potential in DLBCL patients
by: Lingyu Zhang, et al.
Published: (2025-05-01)

Bolstering CD8<sup>+</sup> T Cells’ Antitumor Immunity: A Promising Strategy to Improve the Response to Advanced Prostate Cancer Treatment
by: Beijing Dang, et al.
Published: (2025-05-01)

A preclinical model for the identification of therapeutically active transgenes in local cancer immunotherapy
by: Arne Menze, et al.
Published: (2025-12-01)

Association of Absolute Lymphocyte Count and Circulating CD4+ and CD8+ T-Cells with Positive Clinical Outcome in Survivors of Cancer: An Observational Study
by: Suresh Rao, et al.
Published: (2019-07-01)

Case report of non-gene editing CD7 CAR T cell therapy in CD7+ Sézary syndrome: preclinical validation and first-in-human use
by: Haichan Xu, et al.
Published: (2025-08-01)

Identification of biomarkers associated with exhausted CD8 + T cells in the tumor microenvironment of intrahepatic cholangiocarcinoma based on Mendelian randomization and bioinformatics analysis
by: LiuXing Feng, et al.
Published: (2025-06-01)

Lymph node-targeted delivery of Lonicera japonica thunb. polysaccharides for enhancing antitumor immunotherapy
by: Jiatong Zhang, et al.
Published: (2025-04-01)

Bisecting GlcNAc enhances CD8+ T cell-mediated killing of breast cancer by suppressing PD-L1 expression and its binding to PD-1
by: Xueting Ren, et al.
Published: (2025-08-01)

CD8+ T cell activation in endometrial cancer: prognostic implications and potential for personalized therapy
by: HaoTong Guan, et al.
Published: (2025-04-01)

Single-cell RNA and TCR repertoire analysis identify markers of virus-specific T cells
by: Byung-Kwan Jeong, et al.
Published: (2025-05-01)

Identification of a stromal immunosuppressive barrier orchestrated by SPP1+/C1QC+ macrophages and CD8+ exhausted T cells driving gastric cancer immunotherapy resistance
by: Guichuang Ma, et al.
Published: (2025-07-01)

Immunogenic cell death and bystander killing: expanding the therapeutic potential of modern antibody-drug conjugates
by: Oliver Kepp, et al.
Published: (2025-12-01)

CAR-exosomes derived from immune cells: an emerging nanoscale vanguard in overcoming tumor immunotherapy hurdles
by: Xiaoyan Zhao, et al.
Published: (2025-08-01)

Improving STING agonist-based cancer therapy by inhibiting the autophagy-related protein VPS34
by: Elisabetta Bartolini, et al.
Published: (2024-12-01)

Unleashing anti-tumor immunity: Targeting the autophagy-related protein VPS34 to enhance STING agonist-based therapy
by: Elisabetta Bartolini, et al.
Published: (2024-12-01)

The prognostic marker KRT81 is involved in suppressing CD8 + T cells and predicts immunotherapy response for triple-negative breast cancer
by: Zhideng Yan, et al.
Published: (2024-12-01)

T lymphocyte heterogeneity in NSCLC: implications for biomarker development and therapeutic innovation
by: Yu Liu, et al.
Published: (2025-05-01)

Propionyl-CoA carboxylase subunit B regulates anti-tumor T cells in a pancreatic cancer mouse model
by: Han V Han, et al.
Published: (2025-03-01)

The mechanisms and clinical significance of CD8+ T cell exhaustion in anti-tumor immunity
by: Tao Zhong, et al.
Published: (2025-05-01)

Chromosome Missegregation Triggers Tumor Cell Pyroptosis and Enhances Anti‐Tumor Immunotherapy in Colorectal Cancer
by: Wei Duan, et al.
Published: (2025-03-01)

Ferroptosis of T cell in inflammation and tumour immunity
by: Xueli Xia, et al.
Published: (2025-03-01)

Novel strategies to overcome tumor immunotherapy resistance using CAR NK cells
by: Jun-Hui Guo, et al.
Published: (2025-05-01)

Two chemotherapeutic agents expand stem-like CD62L+CD8+ T cells in antitumor immune responses
by: Xiaokang Ruan, et al.
Published: (2025-04-01)

The function of T cells in immune thrombocytopenia
by: Siyuan Bu, et al.
Published: (2025-02-01)