Filtration Efficiency of Air Conditioner Filters and Face Masks to Limit Exposure to Aerosolized Algal Toxins

Abstract Harmful algal blooms (HABs) can generate toxins that can be aerosolized and negatively impact human health through inhalation. HABs are often found in waterways near residences, therefore, aerosolized HAB toxins can potentially affect both indoor and outdoor air quality. Given that HABs are...

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Main Authors: Cassandra J. Gaston, Haley M. Royer, Raymond J. Leibensperger, Daniela Maizel, Kaycie B. Lanpher, Helena Solo-Gabriele, Larry E. Brand, R. Grace Zhai, Alberto J. Caban-Martinez, Kimberly J. Popendorf
Format: Article
Language:English
Published: Springer 2021-04-01
Series:Aerosol and Air Quality Research
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Online Access:https://doi.org/10.4209/aaqr.210016
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author Cassandra J. Gaston
Haley M. Royer
Raymond J. Leibensperger
Daniela Maizel
Kaycie B. Lanpher
Helena Solo-Gabriele
Larry E. Brand
R. Grace Zhai
Alberto J. Caban-Martinez
Kimberly J. Popendorf
author_facet Cassandra J. Gaston
Haley M. Royer
Raymond J. Leibensperger
Daniela Maizel
Kaycie B. Lanpher
Helena Solo-Gabriele
Larry E. Brand
R. Grace Zhai
Alberto J. Caban-Martinez
Kimberly J. Popendorf
author_sort Cassandra J. Gaston
collection DOAJ
description Abstract Harmful algal blooms (HABs) can generate toxins that can be aerosolized and negatively impact human health through inhalation. HABs are often found in waterways near residences, therefore, aerosolized HAB toxins can potentially affect both indoor and outdoor air quality. Given that HABs are predicted to increase worldwide, effective mitigation strategies are needed to prevent the inhalation of aerosolized HAB toxins. In this work, we characterized both the particle filtration efficiency using particle sizing instruments as well as the mass concentration of different congeners of aerosolized microcystin (MC) toxins that penetrate through commercially available face masks and air conditioner (AC) filters. Particles were generated from cultures of the toxin-producing cyanobacteria Microcystis aeruginosa. Hydrophobic congeners of microcystin including MC-LF and MC-LW were enriched in aerosols compared to water, with MC-LR being the most abundant, which has implications for the toxicity of inhalable particles generated from HAB-contaminated waters. Particle transmission efficiencies and toxin filtration efficiencies scaled with the manufacturer-provided filter performance ratings. Up to 80% of small, microcystin-containing aerosols were transmitted through AC filters with low filter performance ratings. In contrast, both face masks as well as AC filters with high filter performance ratings efficiently removed toxin-containing particles to below limits of quantification. Our findings suggest that face masks and commercially available AC filters with high filtration efficiency ratings are suitable mitigation strategies to avoid indoor and outdoor air exposure to aerosolized HAB toxins. This work also has relevance for reducing airborne exposure to other HAB toxins, non-HAB toxins, pathogens, and viruses, including SARS-CoV-2, the virus responsible for the COVID-19 pandemic.
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spelling doaj-art-b2c027e8afc24416bb29b382dba71e722025-08-20T03:02:21ZengSpringerAerosol and Air Quality Research1680-85842071-14092021-04-0121811210.4209/aaqr.210016Filtration Efficiency of Air Conditioner Filters and Face Masks to Limit Exposure to Aerosolized Algal ToxinsCassandra J. Gaston0Haley M. Royer1Raymond J. Leibensperger2Daniela Maizel3Kaycie B. Lanpher4Helena Solo-Gabriele5Larry E. Brand6R. Grace Zhai7Alberto J. Caban-Martinez8Kimberly J. Popendorf9Rosenstiel School of Marine and Atmospheric Sciences, University of MiamiRosenstiel School of Marine and Atmospheric Sciences, University of MiamiRosenstiel School of Marine and Atmospheric Sciences, University of MiamiRosenstiel School of Marine and Atmospheric Sciences, University of MiamiRosenstiel School of Marine and Atmospheric Sciences, University of MiamiDepartment of Civil, Architectural, and Environmental Engineering, University of MiamiRosenstiel School of Marine and Atmospheric Sciences, University of MiamiDepartment of Molecular and Cellular Pharmacology, University of Miami, Miller School of MedicineDepartment of Public Health Sciences, University of Miami, Miller School of MedicineRosenstiel School of Marine and Atmospheric Sciences, University of MiamiAbstract Harmful algal blooms (HABs) can generate toxins that can be aerosolized and negatively impact human health through inhalation. HABs are often found in waterways near residences, therefore, aerosolized HAB toxins can potentially affect both indoor and outdoor air quality. Given that HABs are predicted to increase worldwide, effective mitigation strategies are needed to prevent the inhalation of aerosolized HAB toxins. In this work, we characterized both the particle filtration efficiency using particle sizing instruments as well as the mass concentration of different congeners of aerosolized microcystin (MC) toxins that penetrate through commercially available face masks and air conditioner (AC) filters. Particles were generated from cultures of the toxin-producing cyanobacteria Microcystis aeruginosa. Hydrophobic congeners of microcystin including MC-LF and MC-LW were enriched in aerosols compared to water, with MC-LR being the most abundant, which has implications for the toxicity of inhalable particles generated from HAB-contaminated waters. Particle transmission efficiencies and toxin filtration efficiencies scaled with the manufacturer-provided filter performance ratings. Up to 80% of small, microcystin-containing aerosols were transmitted through AC filters with low filter performance ratings. In contrast, both face masks as well as AC filters with high filter performance ratings efficiently removed toxin-containing particles to below limits of quantification. Our findings suggest that face masks and commercially available AC filters with high filtration efficiency ratings are suitable mitigation strategies to avoid indoor and outdoor air exposure to aerosolized HAB toxins. This work also has relevance for reducing airborne exposure to other HAB toxins, non-HAB toxins, pathogens, and viruses, including SARS-CoV-2, the virus responsible for the COVID-19 pandemic.https://doi.org/10.4209/aaqr.210016Harmful algal bloomAerosolFilter efficiencyPathogenMicrocystin
spellingShingle Cassandra J. Gaston
Haley M. Royer
Raymond J. Leibensperger
Daniela Maizel
Kaycie B. Lanpher
Helena Solo-Gabriele
Larry E. Brand
R. Grace Zhai
Alberto J. Caban-Martinez
Kimberly J. Popendorf
Filtration Efficiency of Air Conditioner Filters and Face Masks to Limit Exposure to Aerosolized Algal Toxins
Aerosol and Air Quality Research
Harmful algal bloom
Aerosol
Filter efficiency
Pathogen
Microcystin
title Filtration Efficiency of Air Conditioner Filters and Face Masks to Limit Exposure to Aerosolized Algal Toxins
title_full Filtration Efficiency of Air Conditioner Filters and Face Masks to Limit Exposure to Aerosolized Algal Toxins
title_fullStr Filtration Efficiency of Air Conditioner Filters and Face Masks to Limit Exposure to Aerosolized Algal Toxins
title_full_unstemmed Filtration Efficiency of Air Conditioner Filters and Face Masks to Limit Exposure to Aerosolized Algal Toxins
title_short Filtration Efficiency of Air Conditioner Filters and Face Masks to Limit Exposure to Aerosolized Algal Toxins
title_sort filtration efficiency of air conditioner filters and face masks to limit exposure to aerosolized algal toxins
topic Harmful algal bloom
Aerosol
Filter efficiency
Pathogen
Microcystin
url https://doi.org/10.4209/aaqr.210016
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