Prescribing Drugs not in Accordance with the Official Instructions for Medical Use (Off-label), Clinical Guidelines, Standards of Medical Care and Legal Regulation in the Russian Federation. Part 2

Prescribing drugs not in accordance with the official instructions for medical use (off-label) has medical and legal aspects. From a medical point of view, such an appointment can be dictated by clinical urgency, when there is no alternative therapy, and on the other hand, doctors often prescribe of...

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Main Authors: A. R. Navasardyan, S. Yu. Martsevich, P. G. Gabay
Format: Article
Language:English
Published: Столичная издательская компания 2021-05-01
Series:Рациональная фармакотерапия в кардиологии
Subjects:
Online Access:https://www.rpcardio.online/jour/article/view/2439
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author A. R. Navasardyan
S. Yu. Martsevich
P. G. Gabay
author_facet A. R. Navasardyan
S. Yu. Martsevich
P. G. Gabay
author_sort A. R. Navasardyan
collection DOAJ
description Prescribing drugs not in accordance with the official instructions for medical use (off-label) has medical and legal aspects. From a medical point of view, such an appointment can be dictated by clinical urgency, when there is no alternative therapy, and on the other hand, doctors often prescribe off-label drugs unknowingly, and also when there is another drug with registered indications. The article analyzes the regulations governing such appointments. The article describes possible inconsistencies between clinical guidelines and standards of medical care in this matter, the role of the medical commission, the impact on the quality and safety of medical care, as well as the types of legal liability of a medical worker that may arise when a drug is prescribed not according to instructions.
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institution Kabale University
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language English
publishDate 2021-05-01
publisher Столичная издательская компания
record_format Article
series Рациональная фармакотерапия в кардиологии
spelling doaj-art-b2b6fc309cea43c4af19f9cb11fb1b322025-08-23T10:00:33ZengСтоличная издательская компанияРациональная фармакотерапия в кардиологии1819-64462225-36532021-05-0117228629310.20996/1819-6446-2021-04-011878Prescribing Drugs not in Accordance with the Official Instructions for Medical Use (Off-label), Clinical Guidelines, Standards of Medical Care and Legal Regulation in the Russian Federation. Part 2A. R. Navasardyan0S. Yu. Martsevich1P. G. Gabay2Bayer JSCNational Medical Research Center for Therapy and Preventive MedicineFaculty of Medical Law, LLC; Federal Scientific and Clinical Center for Specialized Types of Medical Care and Medical Technologies of the Federal Medical and Biological Agency of RussiaPrescribing drugs not in accordance with the official instructions for medical use (off-label) has medical and legal aspects. From a medical point of view, such an appointment can be dictated by clinical urgency, when there is no alternative therapy, and on the other hand, doctors often prescribe off-label drugs unknowingly, and also when there is another drug with registered indications. The article analyzes the regulations governing such appointments. The article describes possible inconsistencies between clinical guidelines and standards of medical care in this matter, the role of the medical commission, the impact on the quality and safety of medical care, as well as the types of legal liability of a medical worker that may arise when a drug is prescribed not according to instructions.https://www.rpcardio.online/jour/article/view/2439off-label prescription of drugsunregistered druglegal regulationclinical guidelinesquality of medical care
spellingShingle A. R. Navasardyan
S. Yu. Martsevich
P. G. Gabay
Prescribing Drugs not in Accordance with the Official Instructions for Medical Use (Off-label), Clinical Guidelines, Standards of Medical Care and Legal Regulation in the Russian Federation. Part 2
Рациональная фармакотерапия в кардиологии
off-label prescription of drugs
unregistered drug
legal regulation
clinical guidelines
quality of medical care
title Prescribing Drugs not in Accordance with the Official Instructions for Medical Use (Off-label), Clinical Guidelines, Standards of Medical Care and Legal Regulation in the Russian Federation. Part 2
title_full Prescribing Drugs not in Accordance with the Official Instructions for Medical Use (Off-label), Clinical Guidelines, Standards of Medical Care and Legal Regulation in the Russian Federation. Part 2
title_fullStr Prescribing Drugs not in Accordance with the Official Instructions for Medical Use (Off-label), Clinical Guidelines, Standards of Medical Care and Legal Regulation in the Russian Federation. Part 2
title_full_unstemmed Prescribing Drugs not in Accordance with the Official Instructions for Medical Use (Off-label), Clinical Guidelines, Standards of Medical Care and Legal Regulation in the Russian Federation. Part 2
title_short Prescribing Drugs not in Accordance with the Official Instructions for Medical Use (Off-label), Clinical Guidelines, Standards of Medical Care and Legal Regulation in the Russian Federation. Part 2
title_sort prescribing drugs not in accordance with the official instructions for medical use off label clinical guidelines standards of medical care and legal regulation in the russian federation part 2
topic off-label prescription of drugs
unregistered drug
legal regulation
clinical guidelines
quality of medical care
url https://www.rpcardio.online/jour/article/view/2439
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AT syumartsevich prescribingdrugsnotinaccordancewiththeofficialinstructionsformedicaluseofflabelclinicalguidelinesstandardsofmedicalcareandlegalregulationintherussianfederationpart2
AT pggabay prescribingdrugsnotinaccordancewiththeofficialinstructionsformedicaluseofflabelclinicalguidelinesstandardsofmedicalcareandlegalregulationintherussianfederationpart2