Oral Glucose Tolerance Test (OGTT) among type 1 diabetic Siblings and Control group

Background: the genetic factor of type 1 diabetes mellitus may play a key role in pathogenesis of that disorder, thus, diabetic siblings might prone into an impaired OGTT. Objective: To determine whether diabetic Siblings might have an impaired glucose tolerance test in compare to normal control...

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Main Authors: Jaafar Kadem Al-Mousawi, Kareem Thamir Al-Kaabi, Muhamed Ali S. Al-Kabe
Format: Article
Language:English
Published: University of Kufa, Faculty of Nursing 2015-08-01
Series:Kufa Journal for Nursing Sciences
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Online Access:https://journal.uokufa.edu.iq/index.php/kjns/article/view/2600
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author Jaafar Kadem Al-Mousawi
Kareem Thamir Al-Kaabi
Muhamed Ali S. Al-Kabe
author_facet Jaafar Kadem Al-Mousawi
Kareem Thamir Al-Kaabi
Muhamed Ali S. Al-Kabe
author_sort Jaafar Kadem Al-Mousawi
collection DOAJ
description Background: the genetic factor of type 1 diabetes mellitus may play a key role in pathogenesis of that disorder, thus, diabetic siblings might prone into an impaired OGTT. Objective: To determine whether diabetic Siblings might have an impaired glucose tolerance test in compare to normal control group. Methodology: A case-control study was performed on 120 persons, they divided into three group which are diabetic, siblings and control (40 persons in each group), who attended to Al Zahraa Teaching Hospital /Diabetic Center in Al-Kut between the period of April; 2012 till April; 2013. Results: OGTT performed on both diabetic siblings and control, results have showed that the Means of OGTT is highly Significant (P value = 0.000) in both Siblings and Control groups, whereas there were no Significant differences in the Means of differences of OGTT in both tested groups (Siblings and Control), P value = 0.288, although the Mean of differences of OGTT is higher in Siblings group (25.3250) than that in Control group (22.0750). Conclusion: the inheritance factor play a key role in pathogenesis of type 1 diabetes mellitus since, diabetic siblings showed an impaired OGTT. Recommendation: for early detection of diabetes, diabetic siblings must submit to a routine screening test by OGGT.
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spelling doaj-art-b2b63b7c08a749c6b76458f10aeae7042025-08-20T03:10:20ZengUniversity of Kufa, Faculty of NursingKufa Journal for Nursing Sciences2223-40552521-86382015-08-015210.36321/kjns.vi20152.2600Oral Glucose Tolerance Test (OGTT) among type 1 diabetic Siblings and Control groupJaafar Kadem Al-Mousawi0Kareem Thamir Al-Kaabi1Muhamed Ali S. Al-Kabe2University of KufaUniversity of KufaUniversity of Wasit Background: the genetic factor of type 1 diabetes mellitus may play a key role in pathogenesis of that disorder, thus, diabetic siblings might prone into an impaired OGTT. Objective: To determine whether diabetic Siblings might have an impaired glucose tolerance test in compare to normal control group. Methodology: A case-control study was performed on 120 persons, they divided into three group which are diabetic, siblings and control (40 persons in each group), who attended to Al Zahraa Teaching Hospital /Diabetic Center in Al-Kut between the period of April; 2012 till April; 2013. Results: OGTT performed on both diabetic siblings and control, results have showed that the Means of OGTT is highly Significant (P value = 0.000) in both Siblings and Control groups, whereas there were no Significant differences in the Means of differences of OGTT in both tested groups (Siblings and Control), P value = 0.288, although the Mean of differences of OGTT is higher in Siblings group (25.3250) than that in Control group (22.0750). Conclusion: the inheritance factor play a key role in pathogenesis of type 1 diabetes mellitus since, diabetic siblings showed an impaired OGTT. Recommendation: for early detection of diabetes, diabetic siblings must submit to a routine screening test by OGGT. https://journal.uokufa.edu.iq/index.php/kjns/article/view/2600Type 1 diabetes mellitusSiblings OGTT
spellingShingle Jaafar Kadem Al-Mousawi
Kareem Thamir Al-Kaabi
Muhamed Ali S. Al-Kabe
Oral Glucose Tolerance Test (OGTT) among type 1 diabetic Siblings and Control group
Kufa Journal for Nursing Sciences
Type 1 diabetes mellitus
Siblings
OGTT
title Oral Glucose Tolerance Test (OGTT) among type 1 diabetic Siblings and Control group
title_full Oral Glucose Tolerance Test (OGTT) among type 1 diabetic Siblings and Control group
title_fullStr Oral Glucose Tolerance Test (OGTT) among type 1 diabetic Siblings and Control group
title_full_unstemmed Oral Glucose Tolerance Test (OGTT) among type 1 diabetic Siblings and Control group
title_short Oral Glucose Tolerance Test (OGTT) among type 1 diabetic Siblings and Control group
title_sort oral glucose tolerance test ogtt among type 1 diabetic siblings and control group
topic Type 1 diabetes mellitus
Siblings
OGTT
url https://journal.uokufa.edu.iq/index.php/kjns/article/view/2600
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AT kareemthamiralkaabi oralglucosetolerancetestogttamongtype1diabeticsiblingsandcontrolgroup
AT muhamedalisalkabe oralglucosetolerancetestogttamongtype1diabeticsiblingsandcontrolgroup