Ultra-sensitive urinary lipoarabinomannan (LAM) immunoassay for tuberculosis detection: a performance evaluationResearch in context

Ultra-sensitive urinary lipoarabinomannan (LAM) immunoassay for tuberculosis detection: a performance evaluationResearch in context

Summary: Background: The development of rapid non-sputum tests remains a global priority to accelerate Tuberculosis (TB) diagnosis and treatment initiation. The only WHO-recommended rapid diagnostic test (RDT), the Alere Determine TB Lipoarabinomannan Ag (AlereLAM) has suboptimal sensitivity. A lab...

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Bibliographic Details
Main Authors: Qisheng Jiang, Carolyn Duncan, Harisha Ramachandraiah, Ige A. George, Sumanth Gandra, Marcos Perez, Lorraine Lillis, David S. Boyle, Scott Crick, Morten Ruhwald, Srikanth Singamaneni
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:EBioMedicine
Subjects:
Tuberculosis
Lipoarabinomannan
Non-sputum
Diagnostic accuracy
Ultra-sensitive assay
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396425003299
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