<i>TRIM5α</i>/Cyclophilin A-Modified MDBK Cells for Lentiviral-Based Gene Editing

<i>TRIM5α</i>/Cyclophilin A-Modified MDBK Cells for Lentiviral-Based Gene Editing

The human immunodeficiency virus 1 (HIV-1)-based lentivirus has been widely used for genetic modification. However, the efficiency of lentiviral-based gene modification in Madin–Darby bovine kidney (MDBK) cells is considerably limited. In this study, we have shown that siRNA-mediated depletion of &l...

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Bibliographic Details
Main Authors: Lijing Wo, Shuhui Qi, Yongqi Guo, Chao Sun, Xin Yin
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Viruses
Subjects:
MDBK
TRIM5α
CypA
Online Access:https://www.mdpi.com/1999-4915/17/7/876
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