Laminar fluid ejection device enables high yield and preservation of mRNA and SaRNA LNP formulations
Abstract The development of messenger RNA (mRNA) and self-amplifying RNA (saRNA) vaccines has revolutionized modern vaccinology, particularly with the success of lipid nanoparticle (LNP)-based SARS-CoV-2 vaccines. Intranasal administration offers a promising approach for respiratory vaccines, provid...
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| Main Authors: | Chia Hao Ho, Irafasha C. Casmil, Manu Sharma, Tim Rees, Kenza Enright, Nick Allan, Anna K. Blakney |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-05-01
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| Series: | Scientific Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/s41598-025-03309-9 |
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