Local Lidocaine–Prilocaine for Immunisation in Infants
<b>Introduction</b>: Lidocaine–prilocaine cream effectively reduces vaccination pain, improving vaccination adherence and advocating for its routine use in healthcare settings. <b>Methods</b>: This review used PRISMA guidelines and the PICOT format to structure the analysis....
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MDPI AG
2024-11-01
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| Series: | Vaccines |
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| Online Access: | https://www.mdpi.com/2076-393X/12/12/1329 |
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| author | Claudia-Felicia Pop Petronela Coblișan Valentina Sas Cătălina Drugă Paraschiva Cherecheș-Panța |
| author_facet | Claudia-Felicia Pop Petronela Coblișan Valentina Sas Cătălina Drugă Paraschiva Cherecheș-Panța |
| author_sort | Claudia-Felicia Pop |
| collection | DOAJ |
| description | <b>Introduction</b>: Lidocaine–prilocaine cream effectively reduces vaccination pain, improving vaccination adherence and advocating for its routine use in healthcare settings. <b>Methods</b>: This review used PRISMA guidelines and the PICOT format to structure the analysis. The focus was on paediatric patients aged 0–12 months requiring intramuscular vaccinations, comparing the application of lidocaine–prilocaine cream to other interventions or no treatment. Data sources included MEDLINE, PUBMED, EMBASE, BMC, Research GATE, and Cochrane Library. Studies were selected based on predefined inclusion and exclusion criteria, with data extracted regarding participant demographics, pain assessment scales, and study conclusions. The Cochrane Risk of Bias Tool assessed study quality, while statistical analyses evaluated the effectiveness of the intervention. <b>Results</b>: Fifty studies were identified, with nine ultimately included in the analysis, involving 704 participants. The primary outcome was the effectiveness of lidocaine–prilocaine cream in reducing pain after vaccinations. Results showed a significant mean difference of −1.719 in pain scores for infants treated with lidocaine–prilocaine compared to those receiving other interventions. Behavioural indicators, such as crying duration and latency to the first cry, favoured the lidocaine–prilocaine group. <b>Conclusions</b>: Lidocaine–prilocaine cream effectively reduces vaccination pain, supporting its routine use in healthcare settings. Engaging parents can enhance vaccination adherence. Training healthcare professionals on lidocaine–prilocaine cream application and pain scales is vital for improving patient satisfaction. Further research is needed to evaluate the long-term effects of lidocaine–prilocaine cream on vaccination experiences and infant behavioural health. |
| format | Article |
| id | doaj-art-b2b1c6e32a744394aead36b484df2a88 |
| institution | DOAJ |
| issn | 2076-393X |
| language | English |
| publishDate | 2024-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Vaccines |
| spelling | doaj-art-b2b1c6e32a744394aead36b484df2a882025-08-20T02:57:04ZengMDPI AGVaccines2076-393X2024-11-011212132910.3390/vaccines12121329Local Lidocaine–Prilocaine for Immunisation in InfantsClaudia-Felicia Pop0Petronela Coblișan1Valentina Sas2Cătălina Drugă3Paraschiva Cherecheș-Panța4Department of Mother and Child, Nursing Discipline, Iuliu Hațieganu University of Medicine and Pharmacy, 400124 Cluj-Napoca, RomaniaDepartment of Mother and Child, Nursing Discipline, Iuliu Hațieganu University of Medicine and Pharmacy, 400124 Cluj-Napoca, RomaniaThird Pediatric Discipline, Faculty of Medicine, Iuliu Hațieganu University of Medicine and Pharmacy, 400124 Cluj-Napoca, RomaniaGeneral Medical Assistance Program, Faculty of Medicine, Iuliu Hațieganu University of Medicine and Pharmacy, 400124 Cluj-Napoca, RomaniaThird Pediatric Discipline, Faculty of Medicine, Iuliu Hațieganu University of Medicine and Pharmacy, 400124 Cluj-Napoca, Romania<b>Introduction</b>: Lidocaine–prilocaine cream effectively reduces vaccination pain, improving vaccination adherence and advocating for its routine use in healthcare settings. <b>Methods</b>: This review used PRISMA guidelines and the PICOT format to structure the analysis. The focus was on paediatric patients aged 0–12 months requiring intramuscular vaccinations, comparing the application of lidocaine–prilocaine cream to other interventions or no treatment. Data sources included MEDLINE, PUBMED, EMBASE, BMC, Research GATE, and Cochrane Library. Studies were selected based on predefined inclusion and exclusion criteria, with data extracted regarding participant demographics, pain assessment scales, and study conclusions. The Cochrane Risk of Bias Tool assessed study quality, while statistical analyses evaluated the effectiveness of the intervention. <b>Results</b>: Fifty studies were identified, with nine ultimately included in the analysis, involving 704 participants. The primary outcome was the effectiveness of lidocaine–prilocaine cream in reducing pain after vaccinations. Results showed a significant mean difference of −1.719 in pain scores for infants treated with lidocaine–prilocaine compared to those receiving other interventions. Behavioural indicators, such as crying duration and latency to the first cry, favoured the lidocaine–prilocaine group. <b>Conclusions</b>: Lidocaine–prilocaine cream effectively reduces vaccination pain, supporting its routine use in healthcare settings. Engaging parents can enhance vaccination adherence. Training healthcare professionals on lidocaine–prilocaine cream application and pain scales is vital for improving patient satisfaction. Further research is needed to evaluate the long-term effects of lidocaine–prilocaine cream on vaccination experiences and infant behavioural health.https://www.mdpi.com/2076-393X/12/12/1329lidocaine and prilocainevaccinationinfant |
| spellingShingle | Claudia-Felicia Pop Petronela Coblișan Valentina Sas Cătălina Drugă Paraschiva Cherecheș-Panța Local Lidocaine–Prilocaine for Immunisation in Infants Vaccines lidocaine and prilocaine vaccination infant |
| title | Local Lidocaine–Prilocaine for Immunisation in Infants |
| title_full | Local Lidocaine–Prilocaine for Immunisation in Infants |
| title_fullStr | Local Lidocaine–Prilocaine for Immunisation in Infants |
| title_full_unstemmed | Local Lidocaine–Prilocaine for Immunisation in Infants |
| title_short | Local Lidocaine–Prilocaine for Immunisation in Infants |
| title_sort | local lidocaine prilocaine for immunisation in infants |
| topic | lidocaine and prilocaine vaccination infant |
| url | https://www.mdpi.com/2076-393X/12/12/1329 |
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