Classical Hodgkin Lymphoma Presenting as Cutaneous and Soft Tissue Mass Lesion: An Enigmatic Presentation Posing a Diagnostic Challenge—A Case Report and Review of Literature
Hodgkin lymphoma (HL) is primarily a nodal disease. Cutaneous involvement of HL as a presenting feature is extremely rare. Skin involvement is usually seen as a metachronous involvement in the course of disease and is associated with poor prognosis. Primary skin and soft tissue involvement can be co...
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| Format: | Article |
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Thieme Medical and Scientific Publishers Pvt. Ltd.
2024-12-01
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| Series: | Indian Journal of Medical and Paediatric Oncology |
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| Online Access: | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0041-1740441 |
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| author | Ayushi Shrivastava Sandeep Jain Payal Malhotra Shalini Mishra Sunil Pasricha Gauri Kapoor |
| author_facet | Ayushi Shrivastava Sandeep Jain Payal Malhotra Shalini Mishra Sunil Pasricha Gauri Kapoor |
| author_sort | Ayushi Shrivastava |
| collection | DOAJ |
| description | Hodgkin lymphoma (HL) is primarily a nodal disease. Cutaneous involvement of HL as a presenting feature is extremely rare. Skin involvement is usually seen as a metachronous involvement in the course of disease and is associated with poor prognosis. Primary skin and soft tissue involvement can be construed as nonhematological, inflammatory, or infective etiology. We report a 14-year-old girl with fever, weight loss, lymphadenopathy, and multiple papular lesions over the right chest wall as initial manifestation of HL, posing a diagnostic challenge. In view of stage IVBE, patient was managed with intensive chemotherapy regimen and is currently free of disease at 6 months of follow-up. |
| format | Article |
| id | doaj-art-b2b083a2602242f78f4bf13da80eec40 |
| institution | OA Journals |
| issn | 0971-5851 0975-2129 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Thieme Medical and Scientific Publishers Pvt. Ltd. |
| record_format | Article |
| series | Indian Journal of Medical and Paediatric Oncology |
| spelling | doaj-art-b2b083a2602242f78f4bf13da80eec402025-08-20T02:32:41ZengThieme Medical and Scientific Publishers Pvt. Ltd.Indian Journal of Medical and Paediatric Oncology0971-58510975-21292024-12-01450653854110.1055/s-0041-1740441Classical Hodgkin Lymphoma Presenting as Cutaneous and Soft Tissue Mass Lesion: An Enigmatic Presentation Posing a Diagnostic Challenge—A Case Report and Review of LiteratureAyushi Shrivastava0Sandeep Jain1Payal Malhotra2Shalini Mishra3Sunil Pasricha4Gauri Kapoor5Department of Pediatric Hematology Oncology, Rajiv Gandhi Cancer Institute and Research Centre, New Delhi, IndiaDepartment of Pediatric Hematology Oncology, Rajiv Gandhi Cancer Institute and Research Centre, New Delhi, IndiaDepartment of Pediatric Hematology Oncology, Rajiv Gandhi Cancer Institute and Research Centre, New Delhi, IndiaDepartment of Pediatric Surgical Oncology, Rajiv Gandhi Cancer Institute and Research Centre, New Delhi, IndiaDepartment of Pathology, Rajiv Gandhi Cancer Institute and Research Centre, New Delhi, IndiaDepartment of Pediatric Hematology Oncology, Rajiv Gandhi Cancer Institute and Research Centre, New Delhi, IndiaHodgkin lymphoma (HL) is primarily a nodal disease. Cutaneous involvement of HL as a presenting feature is extremely rare. Skin involvement is usually seen as a metachronous involvement in the course of disease and is associated with poor prognosis. Primary skin and soft tissue involvement can be construed as nonhematological, inflammatory, or infective etiology. We report a 14-year-old girl with fever, weight loss, lymphadenopathy, and multiple papular lesions over the right chest wall as initial manifestation of HL, posing a diagnostic challenge. In view of stage IVBE, patient was managed with intensive chemotherapy regimen and is currently free of disease at 6 months of follow-up.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0041-1740441cutaneousextranodalHodgkin lymphoma |
| spellingShingle | Ayushi Shrivastava Sandeep Jain Payal Malhotra Shalini Mishra Sunil Pasricha Gauri Kapoor Classical Hodgkin Lymphoma Presenting as Cutaneous and Soft Tissue Mass Lesion: An Enigmatic Presentation Posing a Diagnostic Challenge—A Case Report and Review of Literature Indian Journal of Medical and Paediatric Oncology cutaneous extranodal Hodgkin lymphoma |
| title | Classical Hodgkin Lymphoma Presenting as Cutaneous and Soft Tissue Mass Lesion: An Enigmatic Presentation Posing a Diagnostic Challenge—A Case Report and Review of Literature |
| title_full | Classical Hodgkin Lymphoma Presenting as Cutaneous and Soft Tissue Mass Lesion: An Enigmatic Presentation Posing a Diagnostic Challenge—A Case Report and Review of Literature |
| title_fullStr | Classical Hodgkin Lymphoma Presenting as Cutaneous and Soft Tissue Mass Lesion: An Enigmatic Presentation Posing a Diagnostic Challenge—A Case Report and Review of Literature |
| title_full_unstemmed | Classical Hodgkin Lymphoma Presenting as Cutaneous and Soft Tissue Mass Lesion: An Enigmatic Presentation Posing a Diagnostic Challenge—A Case Report and Review of Literature |
| title_short | Classical Hodgkin Lymphoma Presenting as Cutaneous and Soft Tissue Mass Lesion: An Enigmatic Presentation Posing a Diagnostic Challenge—A Case Report and Review of Literature |
| title_sort | classical hodgkin lymphoma presenting as cutaneous and soft tissue mass lesion an enigmatic presentation posing a diagnostic challenge a case report and review of literature |
| topic | cutaneous extranodal Hodgkin lymphoma |
| url | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0041-1740441 |
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