The Management of Pregnancy in Women with Hepatocellular Adenoma: A Plea for an Individualized Approach

Because of the risk of hormone-induced growth and spontaneous rupture of hepatocellular adenoma (HCA) during pregnancy, special considerations are required. Due to the scarcity of cases, there is no evidence-based algorithm for the evaluation and management of HCA during pregnancy. We think it shoul...

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Main Authors: Mirelle E. E. Bröker, Jan N. M. Ijzermans, Susanna M. van Aalten, Robert A. de Man, Türkan Terkivatan
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:International Journal of Hepatology
Online Access:http://dx.doi.org/10.1155/2012/725735
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author Mirelle E. E. Bröker
Jan N. M. Ijzermans
Susanna M. van Aalten
Robert A. de Man
Türkan Terkivatan
author_facet Mirelle E. E. Bröker
Jan N. M. Ijzermans
Susanna M. van Aalten
Robert A. de Man
Türkan Terkivatan
author_sort Mirelle E. E. Bröker
collection DOAJ
description Because of the risk of hormone-induced growth and spontaneous rupture of hepatocellular adenoma (HCA) during pregnancy, special considerations are required. Due to the scarcity of cases, there is no evidence-based algorithm for the evaluation and management of HCA during pregnancy. We think it should be questioned if it is justified to discourage pregnancy in all women with HCA. The biological behavior of this benign lesion might be less threatening than presumed and a negative advice concerning pregnancy has great impact on the lives of these young female patients. The balance between the pros and cons of hepatic adenomas and pregnancy should be reconsidered. In our center, pregnancy in women with an HCA up to 5 cm is no longer discouraged in close consultation with the patient, her partner, and members of the liver expert team.
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institution OA Journals
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publishDate 2012-01-01
publisher Wiley
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series International Journal of Hepatology
spelling doaj-art-b2a82f5cfbb44eaa99c618bc08f9efb72025-08-20T02:23:24ZengWileyInternational Journal of Hepatology2090-34482090-34562012-01-01201210.1155/2012/725735725735The Management of Pregnancy in Women with Hepatocellular Adenoma: A Plea for an Individualized ApproachMirelle E. E. Bröker0Jan N. M. Ijzermans1Susanna M. van Aalten2Robert A. de Man3Türkan Terkivatan4Department of Surgery, Erasmus Medical Center, P.O. Box 2040, 3000 CA Rotterdam, The NetherlandsDepartment of Surgery, Erasmus Medical Center, P.O. Box 2040, 3000 CA Rotterdam, The NetherlandsDepartment of Surgery, Erasmus Medical Center, P.O. Box 2040, 3000 CA Rotterdam, The NetherlandsDepartment of Gastroenterology and Hepatology, Erasmus Medical Center, P.O. Box 2040, 3000 CA Rotterdam, The NetherlandsDepartment of Surgery, Erasmus Medical Center, P.O. Box 2040, 3000 CA Rotterdam, The NetherlandsBecause of the risk of hormone-induced growth and spontaneous rupture of hepatocellular adenoma (HCA) during pregnancy, special considerations are required. Due to the scarcity of cases, there is no evidence-based algorithm for the evaluation and management of HCA during pregnancy. We think it should be questioned if it is justified to discourage pregnancy in all women with HCA. The biological behavior of this benign lesion might be less threatening than presumed and a negative advice concerning pregnancy has great impact on the lives of these young female patients. The balance between the pros and cons of hepatic adenomas and pregnancy should be reconsidered. In our center, pregnancy in women with an HCA up to 5 cm is no longer discouraged in close consultation with the patient, her partner, and members of the liver expert team.http://dx.doi.org/10.1155/2012/725735
spellingShingle Mirelle E. E. Bröker
Jan N. M. Ijzermans
Susanna M. van Aalten
Robert A. de Man
Türkan Terkivatan
The Management of Pregnancy in Women with Hepatocellular Adenoma: A Plea for an Individualized Approach
International Journal of Hepatology
title The Management of Pregnancy in Women with Hepatocellular Adenoma: A Plea for an Individualized Approach
title_full The Management of Pregnancy in Women with Hepatocellular Adenoma: A Plea for an Individualized Approach
title_fullStr The Management of Pregnancy in Women with Hepatocellular Adenoma: A Plea for an Individualized Approach
title_full_unstemmed The Management of Pregnancy in Women with Hepatocellular Adenoma: A Plea for an Individualized Approach
title_short The Management of Pregnancy in Women with Hepatocellular Adenoma: A Plea for an Individualized Approach
title_sort management of pregnancy in women with hepatocellular adenoma a plea for an individualized approach
url http://dx.doi.org/10.1155/2012/725735
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