Research advance of N <sup>6</sup>-methyladenosine (m<sup>6</sup>A) in insect

RNA modifications play vital roles in regulating gene expression of eukaryotes. The most prevalent RNA modification among them is N<sup> 6</sup>-methyladenosine (m<sup>6</sup>A), which is involved in a series of physiological activities. The mechanism of m<sup>6</sup...

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Main Authors: ZHAO Shudi, WU Xiaofeng
Format: Article
Language:English
Published: Zhejiang University Press 2021-06-01
Series:浙江大学学报. 农业与生命科学版
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Online Access:https://www.academax.com/doi/10.3785/j.issn.1008-9209.2020.07.152
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author ZHAO Shudi
WU Xiaofeng
author_facet ZHAO Shudi
WU Xiaofeng
author_sort ZHAO Shudi
collection DOAJ
description RNA modifications play vital roles in regulating gene expression of eukaryotes. The most prevalent RNA modification among them is N<sup> 6</sup>-methyladenosine (m<sup>6</sup>A), which is involved in a series of physiological activities. The mechanism of m<sup>6</sup>A regulatory enzymes as well as reader proteins, the process of m<sup>6</sup>A dynamic regulation, and the regular pattern of m<sup>6</sup>A distribution in mRNAs were introduced, and the typical biological functions of m<sup>6</sup>A mainly according to the recent progresses made in insects were summarized. Above the review, we preview the research and application prospects of m<sup>6</sup>A from the aspects of vacancies existing in current study and related phenomenon to be explain, aimed at forming the latest reference for exploration of m<sup>6</sup>A in insects.
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spelling doaj-art-b29a8f449d404ca590adc9e2e27b065f2025-08-20T02:47:32ZengZhejiang University Press浙江大学学报. 农业与生命科学版1008-92092097-51552021-06-014729530210.3785/j.issn.1008-9209.2020.07.15210089209Research advance of N <sup>6</sup>-methyladenosine (m<sup>6</sup>A) in insectZHAO ShudiWU XiaofengRNA modifications play vital roles in regulating gene expression of eukaryotes. The most prevalent RNA modification among them is N<sup> 6</sup>-methyladenosine (m<sup>6</sup>A), which is involved in a series of physiological activities. The mechanism of m<sup>6</sup>A regulatory enzymes as well as reader proteins, the process of m<sup>6</sup>A dynamic regulation, and the regular pattern of m<sup>6</sup>A distribution in mRNAs were introduced, and the typical biological functions of m<sup>6</sup>A mainly according to the recent progresses made in insects were summarized. Above the review, we preview the research and application prospects of m<sup>6</sup>A from the aspects of vacancies existing in current study and related phenomenon to be explain, aimed at forming the latest reference for exploration of m<sup>6</sup>A in insects.https://www.academax.com/doi/10.3785/j.issn.1008-9209.2020.07.152RNA modification<italic>N</italic><sup> 6</sup>-methyladenosine (m<sup>6</sup>A)insectregulatory mechanismfunction
spellingShingle ZHAO Shudi
WU Xiaofeng
Research advance of N <sup>6</sup>-methyladenosine (m<sup>6</sup>A) in insect
浙江大学学报. 农业与生命科学版
RNA modification
<italic>N</italic><sup> 6</sup>-methyladenosine (m<sup>6</sup>A)
insect
regulatory mechanism
function
title Research advance of N <sup>6</sup>-methyladenosine (m<sup>6</sup>A) in insect
title_full Research advance of N <sup>6</sup>-methyladenosine (m<sup>6</sup>A) in insect
title_fullStr Research advance of N <sup>6</sup>-methyladenosine (m<sup>6</sup>A) in insect
title_full_unstemmed Research advance of N <sup>6</sup>-methyladenosine (m<sup>6</sup>A) in insect
title_short Research advance of N <sup>6</sup>-methyladenosine (m<sup>6</sup>A) in insect
title_sort research advance of n sup 6 sup methyladenosine m sup 6 sup a in insect
topic RNA modification
<italic>N</italic><sup> 6</sup>-methyladenosine (m<sup>6</sup>A)
insect
regulatory mechanism
function
url https://www.academax.com/doi/10.3785/j.issn.1008-9209.2020.07.152
work_keys_str_mv AT zhaoshudi researchadvanceofnsup6supmethyladenosinemsup6supaininsect
AT wuxiaofeng researchadvanceofnsup6supmethyladenosinemsup6supaininsect