Yoga Therapy Attenuates the Progression of Diabetes – Insights from Proteomics and Metabolomics Analysis
Objective: Diabetes management remains challenging despite advancements in therapeutics, with many subjects developing complications. Yoga has been shown to aid diabetes management. This study investigates the impact of yoga therapy on diabetes progression, utilizing proteomics and metabolomics anal...
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| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2024-12-01
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| Series: | International Journal of Yoga |
| Subjects: | |
| Online Access: | https://journals.lww.com/10.4103/ijoy.ijoy_178_24 |
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| author | Babasaheb P. Sonwane Pooja Raut Jyotsna Chitalkar Smita Godbole Shanta Sabnis Jyoti Gupta B. Santhakumari Mukund V. Deshpande Mahesh J. Kulkarni |
| author_facet | Babasaheb P. Sonwane Pooja Raut Jyotsna Chitalkar Smita Godbole Shanta Sabnis Jyoti Gupta B. Santhakumari Mukund V. Deshpande Mahesh J. Kulkarni |
| author_sort | Babasaheb P. Sonwane |
| collection | DOAJ |
| description | Objective:
Diabetes management remains challenging despite advancements in therapeutics, with many subjects developing complications. Yoga has been shown to aid diabetes management. This study investigates the impact of yoga therapy on diabetes progression, utilizing proteomics and metabolomics analyses to explore underlying molecular mechanisms.
Methodology:
A 3-month longitudinal study involving healthy subjects with prediabetes and diabetes was conducted. Blood glucose, glycated hemoglobin (HbA1c), lipid profile, and malondialdehyde (MDA) levels were measured before and after the yoga intervention.
Results and Conclusion:
Healthy subjects showed no significant changes in blood glucose, lipid profile, HbA1c, or MDA levels. However, subjects with prediabetes and diabetes experienced positive changes, with decreases in HbA1c and MDA levels. Proteomics and metabolomics analyses provided insights into the molecular mechanisms by which yoga attenuates diabetes progression in subjects with prediabetes and diabetes. This study is a pioneering effort to understand the molecular basis of yoga’s beneficial effects on diabetes management. |
| format | Article |
| id | doaj-art-b2969a49bf924577bb2e608dd29f6150 |
| institution | Kabale University |
| issn | 0973-6131 2231-2714 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | International Journal of Yoga |
| spelling | doaj-art-b2969a49bf924577bb2e608dd29f61502025-01-07T06:37:08ZengWolters Kluwer Medknow PublicationsInternational Journal of Yoga0973-61312231-27142024-12-0117316317410.4103/ijoy.ijoy_178_24Yoga Therapy Attenuates the Progression of Diabetes – Insights from Proteomics and Metabolomics AnalysisBabasaheb P. SonwanePooja RautJyotsna ChitalkarSmita GodboleShanta SabnisJyoti GuptaB. SanthakumariMukund V. DeshpandeMahesh J. KulkarniObjective: Diabetes management remains challenging despite advancements in therapeutics, with many subjects developing complications. Yoga has been shown to aid diabetes management. This study investigates the impact of yoga therapy on diabetes progression, utilizing proteomics and metabolomics analyses to explore underlying molecular mechanisms. Methodology: A 3-month longitudinal study involving healthy subjects with prediabetes and diabetes was conducted. Blood glucose, glycated hemoglobin (HbA1c), lipid profile, and malondialdehyde (MDA) levels were measured before and after the yoga intervention. Results and Conclusion: Healthy subjects showed no significant changes in blood glucose, lipid profile, HbA1c, or MDA levels. However, subjects with prediabetes and diabetes experienced positive changes, with decreases in HbA1c and MDA levels. Proteomics and metabolomics analyses provided insights into the molecular mechanisms by which yoga attenuates diabetes progression in subjects with prediabetes and diabetes. This study is a pioneering effort to understand the molecular basis of yoga’s beneficial effects on diabetes management.https://journals.lww.com/10.4103/ijoy.ijoy_178_24diabetesglycated hemoglobinmetabolomicsproteomicsyoga |
| spellingShingle | Babasaheb P. Sonwane Pooja Raut Jyotsna Chitalkar Smita Godbole Shanta Sabnis Jyoti Gupta B. Santhakumari Mukund V. Deshpande Mahesh J. Kulkarni Yoga Therapy Attenuates the Progression of Diabetes – Insights from Proteomics and Metabolomics Analysis International Journal of Yoga diabetes glycated hemoglobin metabolomics proteomics yoga |
| title | Yoga Therapy Attenuates the Progression of Diabetes – Insights from Proteomics and Metabolomics Analysis |
| title_full | Yoga Therapy Attenuates the Progression of Diabetes – Insights from Proteomics and Metabolomics Analysis |
| title_fullStr | Yoga Therapy Attenuates the Progression of Diabetes – Insights from Proteomics and Metabolomics Analysis |
| title_full_unstemmed | Yoga Therapy Attenuates the Progression of Diabetes – Insights from Proteomics and Metabolomics Analysis |
| title_short | Yoga Therapy Attenuates the Progression of Diabetes – Insights from Proteomics and Metabolomics Analysis |
| title_sort | yoga therapy attenuates the progression of diabetes insights from proteomics and metabolomics analysis |
| topic | diabetes glycated hemoglobin metabolomics proteomics yoga |
| url | https://journals.lww.com/10.4103/ijoy.ijoy_178_24 |
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