3D bioprinting in nasal surgery: a comprehensive review

Abstract Background 3D bioprinting is increasingly recognized as a groundbreaking technology in nasal surgery, offering unprecedented opportunities for precision and customization in surgical planning and reconstruction. The ability to create patient-specific anatomical models, surgical guides, and...

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Main Authors: Balaji Ramamourthy, Namit Kant Singh, Neemu Hage, Krishna Medha Kappagantu, Divya Nayani, Deepashree Srinivasan, Mercy Haokip
Format: Article
Language:English
Published: SpringerOpen 2025-07-01
Series:The Egyptian Journal of Otolaryngology
Subjects:
Online Access:https://doi.org/10.1186/s43163-025-00850-2
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author Balaji Ramamourthy
Namit Kant Singh
Neemu Hage
Krishna Medha Kappagantu
Divya Nayani
Deepashree Srinivasan
Mercy Haokip
author_facet Balaji Ramamourthy
Namit Kant Singh
Neemu Hage
Krishna Medha Kappagantu
Divya Nayani
Deepashree Srinivasan
Mercy Haokip
author_sort Balaji Ramamourthy
collection DOAJ
description Abstract Background 3D bioprinting is increasingly recognized as a groundbreaking technology in nasal surgery, offering unprecedented opportunities for precision and customization in surgical planning and reconstruction. The ability to create patient-specific anatomical models, surgical guides, and bioprinted cartilage scaffolds is reshaping the landscape of both reconstructive and aesthetic nasal procedures. This review examines the current applications and future potential of 3D bioprinting in nasal surgery, with a focus on its role in improving surgical outcomes. Methodology This review employed a comprehensive search strategy to identify relevant studies on 3D bioprinting in nasal surgery. Databases including PubMed, MEDLINE, and Google Scholar were searched using key terms such as “3D bioprinting,” “nasal surgery,” “rhinoplasty,” “nasal cartilage reconstruction,” and “patient-specific models.” The search was limited to peer-reviewed articles published between 2010 and 2024. Studies were selected based on their relevance to surgical planning, anatomical modeling, and bioprinted cartilage scaffolds. Articles discussing technical aspects, clinical outcomes, and future directions were include. Results The review identified that 3D bioprinting significantly enhances surgical precision and outcomes by enabling the creation of highly accurate, patient-specific anatomical models and custom surgical guides. These advancements facilitate detailed preoperative planning, reducing intraoperative risks and improving postoperative results. Additionally, bioprinted cartilage scaffolds show promise in overcoming the limitations of traditional grafting techniques, with potential benefits in tissue integration and patient-specific customization. Conclusion “3D bioprinting is poised to revolutionize nasal surgery, offering tools that enhance both surgical precision and patient outcomes. While challenges such as material biocompatibility, mechanical properties, and regulatory approval persist, ongoing research and technological advancements are expected to address these issues, ultimately leading to wider clinical adoption and improved patient care in nasal surgery.”
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spelling doaj-art-b28456aee5c2416d896d60495fc145f52025-08-20T03:42:23ZengSpringerOpenThe Egyptian Journal of Otolaryngology2090-85392025-07-014111910.1186/s43163-025-00850-23D bioprinting in nasal surgery: a comprehensive reviewBalaji Ramamourthy0Namit Kant Singh1Neemu Hage2Krishna Medha Kappagantu3Divya Nayani4Deepashree Srinivasan5Mercy Haokip6Department of Otorhinolaryngology and Head and Neck Surgery, All India Institute of Medical SciencesDepartment of Otorhinolaryngology and Head and Neck Surgery, All India Institute of Medical SciencesDepartment of Otorhinolaryngology and Head and Neck Surgery, All India Institute of Medical SciencesDepartment of Otorhinolaryngology and Head and Neck Surgery, All India Institute of Medical SciencesDepartment of Otorhinolaryngology and Head and Neck Surgery, All India Institute of Medical SciencesDepartment of Otorhinolaryngology and Head and Neck Surgery, All India Institute of Medical SciencesDepartment of Otorhinolaryngology and Head and Neck Surgery, All India Institute of Medical SciencesAbstract Background 3D bioprinting is increasingly recognized as a groundbreaking technology in nasal surgery, offering unprecedented opportunities for precision and customization in surgical planning and reconstruction. The ability to create patient-specific anatomical models, surgical guides, and bioprinted cartilage scaffolds is reshaping the landscape of both reconstructive and aesthetic nasal procedures. This review examines the current applications and future potential of 3D bioprinting in nasal surgery, with a focus on its role in improving surgical outcomes. Methodology This review employed a comprehensive search strategy to identify relevant studies on 3D bioprinting in nasal surgery. Databases including PubMed, MEDLINE, and Google Scholar were searched using key terms such as “3D bioprinting,” “nasal surgery,” “rhinoplasty,” “nasal cartilage reconstruction,” and “patient-specific models.” The search was limited to peer-reviewed articles published between 2010 and 2024. Studies were selected based on their relevance to surgical planning, anatomical modeling, and bioprinted cartilage scaffolds. Articles discussing technical aspects, clinical outcomes, and future directions were include. Results The review identified that 3D bioprinting significantly enhances surgical precision and outcomes by enabling the creation of highly accurate, patient-specific anatomical models and custom surgical guides. These advancements facilitate detailed preoperative planning, reducing intraoperative risks and improving postoperative results. Additionally, bioprinted cartilage scaffolds show promise in overcoming the limitations of traditional grafting techniques, with potential benefits in tissue integration and patient-specific customization. Conclusion “3D bioprinting is poised to revolutionize nasal surgery, offering tools that enhance both surgical precision and patient outcomes. While challenges such as material biocompatibility, mechanical properties, and regulatory approval persist, ongoing research and technological advancements are expected to address these issues, ultimately leading to wider clinical adoption and improved patient care in nasal surgery.”https://doi.org/10.1186/s43163-025-00850-2CartilageBioprintingTissue engineeringChondrocytesExtracellular matrixHydrogels
spellingShingle Balaji Ramamourthy
Namit Kant Singh
Neemu Hage
Krishna Medha Kappagantu
Divya Nayani
Deepashree Srinivasan
Mercy Haokip
3D bioprinting in nasal surgery: a comprehensive review
The Egyptian Journal of Otolaryngology
Cartilage
Bioprinting
Tissue engineering
Chondrocytes
Extracellular matrix
Hydrogels
title 3D bioprinting in nasal surgery: a comprehensive review
title_full 3D bioprinting in nasal surgery: a comprehensive review
title_fullStr 3D bioprinting in nasal surgery: a comprehensive review
title_full_unstemmed 3D bioprinting in nasal surgery: a comprehensive review
title_short 3D bioprinting in nasal surgery: a comprehensive review
title_sort 3d bioprinting in nasal surgery a comprehensive review
topic Cartilage
Bioprinting
Tissue engineering
Chondrocytes
Extracellular matrix
Hydrogels
url https://doi.org/10.1186/s43163-025-00850-2
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