MXene-Based Electrochemical Biosensors: Advancing Detection Strategies for Biosensing (2020–2024)

MXenes, a class of two-dimensional materials, have emerged as promising candidates for developing advanced electrochemical biosensors due to their exceptional electrical conductivity, large surface area, and rich surface chemistry. These unique properties enable high sensitivity, rapid response, and...

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Main Authors: Joydip Sengupta, Chaudhery Mustansar Hussain
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Biosensors
Subjects:
Online Access:https://www.mdpi.com/2079-6374/15/3/127
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author Joydip Sengupta
Chaudhery Mustansar Hussain
author_facet Joydip Sengupta
Chaudhery Mustansar Hussain
author_sort Joydip Sengupta
collection DOAJ
description MXenes, a class of two-dimensional materials, have emerged as promising candidates for developing advanced electrochemical biosensors due to their exceptional electrical conductivity, large surface area, and rich surface chemistry. These unique properties enable high sensitivity, rapid response, and versatile functionalization, making MXene-based biosensors highly suitable for detecting biomolecules and pathogens in biomedical applications. This review explores recent advancements in MXene-based electrochemical biosensors from 2020 to 2024, focusing on their design principles, fabrication strategies, and integration with microfluidic platforms for enhanced performance. The potential of MXene sensors to achieve real-time and multiplexed detection is highlighted, alongside the associated challenges. Emphasis is placed on the role of MXenes in addressing critical needs in disease diagnostics, personalized medicine, and point-of-care testing, providing insights into future trends and transformative possibilities in the field of biomedical sensing technologies.
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series Biosensors
spelling doaj-art-b279cd0e4a0e439791ac0fb248b1a5bb2025-08-20T03:43:37ZengMDPI AGBiosensors2079-63742025-02-0115312710.3390/bios15030127MXene-Based Electrochemical Biosensors: Advancing Detection Strategies for Biosensing (2020–2024)Joydip Sengupta0Chaudhery Mustansar Hussain1Department of Electronic Science, Jogesh Chandra Chaudhuri College, Kolkata 700033, IndiaDepartment of Chemistry and Environmental Science, New Jersey Institute of Technology, Newark, NJ 07102, USAMXenes, a class of two-dimensional materials, have emerged as promising candidates for developing advanced electrochemical biosensors due to their exceptional electrical conductivity, large surface area, and rich surface chemistry. These unique properties enable high sensitivity, rapid response, and versatile functionalization, making MXene-based biosensors highly suitable for detecting biomolecules and pathogens in biomedical applications. This review explores recent advancements in MXene-based electrochemical biosensors from 2020 to 2024, focusing on their design principles, fabrication strategies, and integration with microfluidic platforms for enhanced performance. The potential of MXene sensors to achieve real-time and multiplexed detection is highlighted, alongside the associated challenges. Emphasis is placed on the role of MXenes in addressing critical needs in disease diagnostics, personalized medicine, and point-of-care testing, providing insights into future trends and transformative possibilities in the field of biomedical sensing technologies.https://www.mdpi.com/2079-6374/15/3/127MXeneselectrochemical biosensorsbiomedical applicationscancer biomarkerpathogensbodily metabolites
spellingShingle Joydip Sengupta
Chaudhery Mustansar Hussain
MXene-Based Electrochemical Biosensors: Advancing Detection Strategies for Biosensing (2020–2024)
Biosensors
MXenes
electrochemical biosensors
biomedical applications
cancer biomarker
pathogens
bodily metabolites
title MXene-Based Electrochemical Biosensors: Advancing Detection Strategies for Biosensing (2020–2024)
title_full MXene-Based Electrochemical Biosensors: Advancing Detection Strategies for Biosensing (2020–2024)
title_fullStr MXene-Based Electrochemical Biosensors: Advancing Detection Strategies for Biosensing (2020–2024)
title_full_unstemmed MXene-Based Electrochemical Biosensors: Advancing Detection Strategies for Biosensing (2020–2024)
title_short MXene-Based Electrochemical Biosensors: Advancing Detection Strategies for Biosensing (2020–2024)
title_sort mxene based electrochemical biosensors advancing detection strategies for biosensing 2020 2024
topic MXenes
electrochemical biosensors
biomedical applications
cancer biomarker
pathogens
bodily metabolites
url https://www.mdpi.com/2079-6374/15/3/127
work_keys_str_mv AT joydipsengupta mxenebasedelectrochemicalbiosensorsadvancingdetectionstrategiesforbiosensing20202024
AT chaudherymustansarhussain mxenebasedelectrochemicalbiosensorsadvancingdetectionstrategiesforbiosensing20202024