A compositional look at the human gastrointestinal microbiome and immune activation parameters in HIV infected subjects.

A compositional look at the human gastrointestinal microbiome and immune activation parameters in HIV infected subjects.

HIV progression is characterized by immune activation and microbial translocation. One factor that may be contributing to HIV progression could be a dysbiotic microbiome. We therefore hypothesized that the GI mucosal microbiome is altered in HIV patients and this alteration correlates with immune ac...

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Main Authors: Ece A Mutlu, Ali Keshavarzian, John Losurdo, Garth Swanson, Basile Siewe, Christopher Forsyth, Audrey French, Patricia Demarais, Yan Sun, Lars Koenig, Stephen Cox, Phillip Engen, Prachi Chakradeo, Rawan Abbasi, Annika Gorenz, Charles Burns, Alan Landay
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-02-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1003829&type=printable
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