Immunogenomic determinants of tumor microenvironment correlate with superior survival in high-risk neuroblastoma
Background Tumor-infiltrating CD8+ T cells and neoantigens are predictors of a favorable prognosis and response to immunotherapy with checkpoint inhibitors in many types of adult cancer, but little is known about their role in pediatric malignancies. Here, we analyzed the prognostic strength of T ce...
Saved in:
| Main Authors: | Ami V Desai, Stefani Spranger, Thomas F Gajewski, Yuanyuan Zha, Jason J Luke, Peter Pytel, Kyle Hernandez, Samuel L Volchenboum, Susan L Cohn |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMJ Publishing Group
2021-07-01
|
| Series: | Journal for ImmunoTherapy of Cancer |
| Online Access: | https://jitc.bmj.com/content/9/7/e002417.full |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Immunogenomic-Based Analysis of Hierarchical Clustering of Diffuse Large Cell Lymphoma
by: Longhao Wang, et al.
Published: (2022-01-01) -
Classification of renal cell carcinoma based on immunogenomic profiling
by: Yanfei Chen, et al.
Published: (2025-12-01) -
Spatial immunogenomic patterns associated with lymph node metastasis in lung adenocarcinoma
by: Fanjie Meng, et al.
Published: (2024-10-01) -
A comprehensive, multi-center, immunogenomic analysis of melanoma brain metastases
by: Lucy Boyce Kennedy, et al.
Published: (2025-06-01) -
T cells in the microenvironment of solid pediatric tumors: the case of neuroblastoma
by: Enrico Maggi, et al.
Published: (2025-02-01)