Sex-specific associations of sex hormone binding globulin and risk of bladder cancer
Males have a three times higher risk of a diagnosis of bladder cancer (Bca) than females. Sex hormone-binding globulin (SHBG) may be associated with Bca risk. However, the sex-specific role of SHBG in Bca remains unclear. In this study, we aimed to determine the role of SHBG in Bca.
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| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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De Gruyter
2025-02-01
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| Series: | Open Medicine |
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| Online Access: | https://doi.org/10.1515/med-2025-1163 |
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| _version_ | 1850240148851130368 |
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| author | Ou Junyong Bi Hai Zhou Haobin Zhang Zhanyi Duan Peichen Yin Haoming Zhou Zezhen Xie Zhixin Tian Xiaojun Ye Jianfei Zhang Shudong |
| author_facet | Ou Junyong Bi Hai Zhou Haobin Zhang Zhanyi Duan Peichen Yin Haoming Zhou Zezhen Xie Zhixin Tian Xiaojun Ye Jianfei Zhang Shudong |
| author_sort | Ou Junyong |
| collection | DOAJ |
| description | Males have a three times higher risk of a diagnosis of bladder cancer (Bca) than females. Sex hormone-binding globulin (SHBG) may be associated with Bca risk. However, the sex-specific role of SHBG in Bca remains unclear. In this study, we aimed to determine the role of SHBG in Bca. |
| format | Article |
| id | doaj-art-b247e8092ca24a3aab37f59fe3ef6b49 |
| institution | OA Journals |
| issn | 2391-5463 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | De Gruyter |
| record_format | Article |
| series | Open Medicine |
| spelling | doaj-art-b247e8092ca24a3aab37f59fe3ef6b492025-08-20T02:00:55ZengDe GruyterOpen Medicine2391-54632025-02-012019610810.1515/med-2025-1163Sex-specific associations of sex hormone binding globulin and risk of bladder cancerOu Junyong0Bi Hai1Zhou Haobin2Zhang Zhanyi3Duan Peichen4Yin Haoming5Zhou Zezhen6Xie Zhixin7Tian Xiaojun8Ye Jianfei9Zhang Shudong10Department of Urology, Peking University Third Hospital, Peking University Health Science Center, Beijing, 100191, ChinaDepartment of Urology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, ChinaThe First Clinical College of Guangzhou Medical University, Guangzhou, Guangdong, 511436, ChinaDepartment of Urology, Peking University Third Hospital, Peking University Health Science Center, Beijing, 100191, ChinaDepartment of Urology, Peking University Third Hospital, Peking University Health Science Center, Beijing, 100191, ChinaDepartment of Urology, Peking University Third Hospital, Peking University Health Science Center, Beijing, 100191, ChinaDepartment of Urology, Peking University Third Hospital, Peking University Health Science Center, Beijing, 100191, ChinaThe Second Clinical College of Guangzhou Medical University, Guangzhou, Guangdong, 511436, ChinaDepartment of Urology, Peking University Third Hospital, Peking University Health Science Center, Beijing, 100191, ChinaDepartment of Urology, Peking University Third Hospital, Peking University Health Science Center, 49 North Garden Road, Beijing, 100191, ChinaDepartment of Urology, Peking University Third Hospital, Peking University Health Science Center, 49 North Garden Road, Beijing, 100191, ChinaMales have a three times higher risk of a diagnosis of bladder cancer (Bca) than females. Sex hormone-binding globulin (SHBG) may be associated with Bca risk. However, the sex-specific role of SHBG in Bca remains unclear. In this study, we aimed to determine the role of SHBG in Bca.https://doi.org/10.1515/med-2025-1163bladder cancersex hormone binding globulinrisktestosteronegenome-wide association studies |
| spellingShingle | Ou Junyong Bi Hai Zhou Haobin Zhang Zhanyi Duan Peichen Yin Haoming Zhou Zezhen Xie Zhixin Tian Xiaojun Ye Jianfei Zhang Shudong Sex-specific associations of sex hormone binding globulin and risk of bladder cancer Open Medicine bladder cancer sex hormone binding globulin risk testosterone genome-wide association studies |
| title | Sex-specific associations of sex hormone binding globulin and risk of bladder cancer |
| title_full | Sex-specific associations of sex hormone binding globulin and risk of bladder cancer |
| title_fullStr | Sex-specific associations of sex hormone binding globulin and risk of bladder cancer |
| title_full_unstemmed | Sex-specific associations of sex hormone binding globulin and risk of bladder cancer |
| title_short | Sex-specific associations of sex hormone binding globulin and risk of bladder cancer |
| title_sort | sex specific associations of sex hormone binding globulin and risk of bladder cancer |
| topic | bladder cancer sex hormone binding globulin risk testosterone genome-wide association studies |
| url | https://doi.org/10.1515/med-2025-1163 |
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