Sex-specific associations of sex hormone binding globulin and risk of bladder cancer

Sex-specific associations of sex hormone binding globulin and risk of bladder cancer

Males have a three times higher risk of a diagnosis of bladder cancer (Bca) than females. Sex hormone-binding globulin (SHBG) may be associated with Bca risk. However, the sex-specific role of SHBG in Bca remains unclear. In this study, we aimed to determine the role of SHBG in Bca.

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Bibliographic Details
Main Authors: Ou Junyong, Bi Hai, Zhou Haobin, Zhang Zhanyi, Duan Peichen, Yin Haoming, Zhou Zezhen, Xie Zhixin, Tian Xiaojun, Ye Jianfei, Zhang Shudong
Format: Article
Language:English
Published: De Gruyter 2025-02-01
Series:Open Medicine
Subjects:
bladder cancer
sex hormone binding globulin
risk
testosterone
genome-wide association studies
Online Access:https://doi.org/10.1515/med-2025-1163
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Summary:Males have a three times higher risk of a diagnosis of bladder cancer (Bca) than females. Sex hormone-binding globulin (SHBG) may be associated with Bca risk. However, the sex-specific role of SHBG in Bca remains unclear. In this study, we aimed to determine the role of SHBG in Bca.
ISSN:2391-5463

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