3D Echocardiographic Assessment of Right Ventricular Involvement of Left Ventricular Hypertrabecularization from a New Perspective

Right ventricular (RV) involvement in left ventricular hypertrabeculation (LVNC) remains under investigation. Due to its complex anatomy, assessing RV function is challenging, but 3D transthoracic echocardiography (3D_TTE) offers valuable insights. We aimed to evaluate volumetric, functional, and st...

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Main Authors: Márton Horváth, Kristóf Farkas-Sütő, Flóra Klára Gyulánczi, Alexandra Fábián, Bálint Lakatos, Anna Réka Kiss, Kinga Grebur, Zsófia Gregor, Balázs Mester, Attila Kovács, Béla Merkely, Andrea Szűcs
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Journal of Imaging
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Online Access:https://www.mdpi.com/2313-433X/11/6/181
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author Márton Horváth
Kristóf Farkas-Sütő
Flóra Klára Gyulánczi
Alexandra Fábián
Bálint Lakatos
Anna Réka Kiss
Kinga Grebur
Zsófia Gregor
Balázs Mester
Attila Kovács
Béla Merkely
Andrea Szűcs
author_facet Márton Horváth
Kristóf Farkas-Sütő
Flóra Klára Gyulánczi
Alexandra Fábián
Bálint Lakatos
Anna Réka Kiss
Kinga Grebur
Zsófia Gregor
Balázs Mester
Attila Kovács
Béla Merkely
Andrea Szűcs
author_sort Márton Horváth
collection DOAJ
description Right ventricular (RV) involvement in left ventricular hypertrabeculation (LVNC) remains under investigation. Due to its complex anatomy, assessing RV function is challenging, but 3D transthoracic echocardiography (3D_TTE) offers valuable insights. We aimed to evaluate volumetric, functional, and strain parameters of both ventricles in LVNC patients with preserved left ventricular ejection fraction (EF) and compare findings to a control group. This study included 37 LVNC patients and 37 age- and sex-matched controls. 3D_TTE recordings were analyzed using TomTec Image Arena (v. 4.7) and reVISION software to assess volumes, EF, and global/segmental strains. RV EF was further divided into longitudinal (LEF), radial (REF), and antero-posterior (AEF) components. LV volumes were significantly higher in the LVNC group, while RV volumes were comparable. EF and strain values were lower in both ventricles in LVNC patients. RV movement analysis showed significantly reduced LEF and REF, whereas AEF remained normal. These findings suggest subclinical RV dysfunction in LVNC, emphasizing the need for follow-up, even with preserved EF.
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spelling doaj-art-b244c6a2ed254c7f84305a2e7bf1d7c22025-08-20T02:20:58ZengMDPI AGJournal of Imaging2313-433X2025-06-0111618110.3390/jimaging110601813D Echocardiographic Assessment of Right Ventricular Involvement of Left Ventricular Hypertrabecularization from a New PerspectiveMárton Horváth0Kristóf Farkas-Sütő1Flóra Klára Gyulánczi2Alexandra Fábián3Bálint Lakatos4Anna Réka Kiss5Kinga Grebur6Zsófia Gregor7Balázs Mester8Attila Kovács9Béla Merkely10Andrea Szűcs11Heart and Vascular Center, Semmelweis University, H-1122 Budapest, HungaryHeart and Vascular Center, Semmelweis University, H-1122 Budapest, HungaryHeart and Vascular Center, Semmelweis University, H-1122 Budapest, HungaryHeart and Vascular Center, Semmelweis University, H-1122 Budapest, HungaryHeart and Vascular Center, Semmelweis University, H-1122 Budapest, HungaryHeart and Vascular Center, Semmelweis University, H-1122 Budapest, HungaryHeart and Vascular Center, Semmelweis University, H-1122 Budapest, HungaryHeart and Vascular Center, Semmelweis University, H-1122 Budapest, HungaryHeart and Vascular Center, Semmelweis University, H-1122 Budapest, HungaryHeart and Vascular Center, Semmelweis University, H-1122 Budapest, HungaryHeart and Vascular Center, Semmelweis University, H-1122 Budapest, HungaryHeart and Vascular Center, Semmelweis University, H-1122 Budapest, HungaryRight ventricular (RV) involvement in left ventricular hypertrabeculation (LVNC) remains under investigation. Due to its complex anatomy, assessing RV function is challenging, but 3D transthoracic echocardiography (3D_TTE) offers valuable insights. We aimed to evaluate volumetric, functional, and strain parameters of both ventricles in LVNC patients with preserved left ventricular ejection fraction (EF) and compare findings to a control group. This study included 37 LVNC patients and 37 age- and sex-matched controls. 3D_TTE recordings were analyzed using TomTec Image Arena (v. 4.7) and reVISION software to assess volumes, EF, and global/segmental strains. RV EF was further divided into longitudinal (LEF), radial (REF), and antero-posterior (AEF) components. LV volumes were significantly higher in the LVNC group, while RV volumes were comparable. EF and strain values were lower in both ventricles in LVNC patients. RV movement analysis showed significantly reduced LEF and REF, whereas AEF remained normal. These findings suggest subclinical RV dysfunction in LVNC, emphasizing the need for follow-up, even with preserved EF.https://www.mdpi.com/2313-433X/11/6/181hypertrabeculationright ventricle3D echocardiography
spellingShingle Márton Horváth
Kristóf Farkas-Sütő
Flóra Klára Gyulánczi
Alexandra Fábián
Bálint Lakatos
Anna Réka Kiss
Kinga Grebur
Zsófia Gregor
Balázs Mester
Attila Kovács
Béla Merkely
Andrea Szűcs
3D Echocardiographic Assessment of Right Ventricular Involvement of Left Ventricular Hypertrabecularization from a New Perspective
Journal of Imaging
hypertrabeculation
right ventricle
3D echocardiography
title 3D Echocardiographic Assessment of Right Ventricular Involvement of Left Ventricular Hypertrabecularization from a New Perspective
title_full 3D Echocardiographic Assessment of Right Ventricular Involvement of Left Ventricular Hypertrabecularization from a New Perspective
title_fullStr 3D Echocardiographic Assessment of Right Ventricular Involvement of Left Ventricular Hypertrabecularization from a New Perspective
title_full_unstemmed 3D Echocardiographic Assessment of Right Ventricular Involvement of Left Ventricular Hypertrabecularization from a New Perspective
title_short 3D Echocardiographic Assessment of Right Ventricular Involvement of Left Ventricular Hypertrabecularization from a New Perspective
title_sort 3d echocardiographic assessment of right ventricular involvement of left ventricular hypertrabecularization from a new perspective
topic hypertrabeculation
right ventricle
3D echocardiography
url https://www.mdpi.com/2313-433X/11/6/181
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