A potent broad-spectrum neutralizing antibody targeting a conserved region of the prefusion RSV F protein

A potent broad-spectrum neutralizing antibody targeting a conserved region of the prefusion RSV F protein

Abstract Respiratory syncytial virus (RSV) poses a significant public health challenge, especially among children. Although palivizumab and nirsevimab, neutralizing antibodies (nAbs) targeting the RSV F protein, have been used for prophylaxis, their limitations underscore the need for more effective...

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Main Authors: Yongpeng Sun, Liqin Liu, Hongsheng Qiang, Hui Sun, Yichao Jiang, Luo Ren, Zemin Jiang, Siyu Lei, Li Chen, Yizhen Wang, Xue Lin, Guosong Wang, Yang Huang, Yuhao Fu, Yujin Shi, Xiuting Chen, Hai Yu, Shaowei Li, Wenxin Luo, Enmei Liu, Qingbing Zheng, Zizheng Zheng, Ningshao Xia
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-54384-x
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