Digital measures of activity and motivation impact depression and anxiety in the real world
Abstract Mood and anxiety disorders are highly comorbid, with symptom severity varying over time. Individuals with and without these disorders completed 30-days of ecological momentary assessment (EMAs) of depression, anxiety and distress, developed based on the established Mood and Anxiety Symptom...
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| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2025-05-01
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| Series: | npj Digital Medicine |
| Online Access: | https://doi.org/10.1038/s41746-025-01669-0 |
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| _version_ | 1849311978320822272 |
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| author | Jacqueline M. Beltrán Yael Jacob Marishka M. Mehta Tasnim Hossain Abigail Adams Samantha Fontaine John Torous Catherine McDonough Matthew Johnson Andrew D. Delgado James W. Murrough Laurel S. Morris |
| author_facet | Jacqueline M. Beltrán Yael Jacob Marishka M. Mehta Tasnim Hossain Abigail Adams Samantha Fontaine John Torous Catherine McDonough Matthew Johnson Andrew D. Delgado James W. Murrough Laurel S. Morris |
| author_sort | Jacqueline M. Beltrán |
| collection | DOAJ |
| description | Abstract Mood and anxiety disorders are highly comorbid, with symptom severity varying over time. Individuals with and without these disorders completed 30-days of ecological momentary assessment (EMAs) of depression, anxiety and distress, developed based on the established Mood and Anxiety Symptom Questionnaire (MASQ). These electronic MASQ (eMASQ) EMAs were collected alongside novel intrinsic and extrinsic motivation EMAs, and physical/digital activity measures (steps/screentime) across N = 70–101 participants. Each eMASQ-EMA significantly related to its corresponding MASQ measure. Extrinsic and intrinsic motivation negatively related to each eMASQ-EMA and had the greatest influence on patients’ overall symptom profile. Physical, but not digital activity, was negatively associated with concurrent and 1-week lagged anxiety and depression, highlighting the temporally delayed benefits of physical activity on depression and anxiety symptoms in psychiatric groups. Collectively, this study suggests cognitive constructs related to drive and physical activity, may be useful in predicting continuous and transient psychiatric symptoms in the real-world. |
| format | Article |
| id | doaj-art-b23a8aed019842ee8cbe31fbce664e3f |
| institution | Kabale University |
| issn | 2398-6352 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | npj Digital Medicine |
| spelling | doaj-art-b23a8aed019842ee8cbe31fbce664e3f2025-08-20T03:53:13ZengNature Portfolionpj Digital Medicine2398-63522025-05-018111510.1038/s41746-025-01669-0Digital measures of activity and motivation impact depression and anxiety in the real worldJacqueline M. Beltrán0Yael Jacob1Marishka M. Mehta2Tasnim Hossain3Abigail Adams4Samantha Fontaine5John Torous6Catherine McDonough7Matthew Johnson8Andrew D. Delgado9James W. Murrough10Laurel S. Morris11Department of Psychiatry, Icahn School of Medicine at Mount SinaiDepartment of Psychiatry, Icahn School of Medicine at Mount SinaiDepartment of Psychiatry, Icahn School of Medicine at Mount SinaiDepartment of Psychiatry, Icahn School of Medicine at Mount SinaiDepartment of Psychiatry, Icahn School of Medicine at Mount SinaiDepartment of Psychiatry, Icahn School of Medicine at Mount SinaiBeth Israel Deaconess Medical Center, Harvard Medical SchoolDepartment of Population Health Science & Policy, Icahn School of Medicine at Mount SinaiThe Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount SinaiDepartment of Population Health Science & Policy, Icahn School of Medicine at Mount SinaiDepartment of Psychiatry, Icahn School of Medicine at Mount SinaiDepartment of Psychiatry, Icahn School of Medicine at Mount SinaiAbstract Mood and anxiety disorders are highly comorbid, with symptom severity varying over time. Individuals with and without these disorders completed 30-days of ecological momentary assessment (EMAs) of depression, anxiety and distress, developed based on the established Mood and Anxiety Symptom Questionnaire (MASQ). These electronic MASQ (eMASQ) EMAs were collected alongside novel intrinsic and extrinsic motivation EMAs, and physical/digital activity measures (steps/screentime) across N = 70–101 participants. Each eMASQ-EMA significantly related to its corresponding MASQ measure. Extrinsic and intrinsic motivation negatively related to each eMASQ-EMA and had the greatest influence on patients’ overall symptom profile. Physical, but not digital activity, was negatively associated with concurrent and 1-week lagged anxiety and depression, highlighting the temporally delayed benefits of physical activity on depression and anxiety symptoms in psychiatric groups. Collectively, this study suggests cognitive constructs related to drive and physical activity, may be useful in predicting continuous and transient psychiatric symptoms in the real-world.https://doi.org/10.1038/s41746-025-01669-0 |
| spellingShingle | Jacqueline M. Beltrán Yael Jacob Marishka M. Mehta Tasnim Hossain Abigail Adams Samantha Fontaine John Torous Catherine McDonough Matthew Johnson Andrew D. Delgado James W. Murrough Laurel S. Morris Digital measures of activity and motivation impact depression and anxiety in the real world npj Digital Medicine |
| title | Digital measures of activity and motivation impact depression and anxiety in the real world |
| title_full | Digital measures of activity and motivation impact depression and anxiety in the real world |
| title_fullStr | Digital measures of activity and motivation impact depression and anxiety in the real world |
| title_full_unstemmed | Digital measures of activity and motivation impact depression and anxiety in the real world |
| title_short | Digital measures of activity and motivation impact depression and anxiety in the real world |
| title_sort | digital measures of activity and motivation impact depression and anxiety in the real world |
| url | https://doi.org/10.1038/s41746-025-01669-0 |
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