Increased Anxiety, Akathisia, and Suicidal Thoughts in Patients with Mood Disorder on Aripiprazole and Lamotrigine
Introduction. Akathisia affects around 18% of patients with bipolar disorder treated with aripiprazole and may worsen when aripiprazole is combined with lamotrigine and antidepressants. Case. This paper reports on two clinical cases involving patients with a diagnosis of mood disorder who developed...
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | Case Reports in Psychiatry |
| Online Access: | http://dx.doi.org/10.1155/2015/419746 |
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| author | Milena Pereira Pondé Antonio Carlos Cruz Freire |
| author_facet | Milena Pereira Pondé Antonio Carlos Cruz Freire |
| author_sort | Milena Pereira Pondé |
| collection | DOAJ |
| description | Introduction. Akathisia affects around 18% of patients with bipolar disorder treated with aripiprazole and may worsen when aripiprazole is combined with lamotrigine and antidepressants. Case. This paper reports on two clinical cases involving patients with a diagnosis of mood disorder who developed severe akathisia, anxiety, and suicidal ideation while using a combination of aripiprazole, antidepressants, and lamotrigine. Discussion. We recommend that patients with a mood disorder taking multiple drugs should begin aripiprazole therapy with low doses and be monitored for the development of akathisia, increased anxiety, or suicidal thoughts. The appearance of these limiting side effects requires discontinuation of the drug. |
| format | Article |
| id | doaj-art-b23a870d378748419678bd63d436fc85 |
| institution | Kabale University |
| issn | 2090-682X 2090-6838 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Psychiatry |
| spelling | doaj-art-b23a870d378748419678bd63d436fc852025-02-03T01:30:04ZengWileyCase Reports in Psychiatry2090-682X2090-68382015-01-01201510.1155/2015/419746419746Increased Anxiety, Akathisia, and Suicidal Thoughts in Patients with Mood Disorder on Aripiprazole and LamotrigineMilena Pereira Pondé0Antonio Carlos Cruz Freire1BAHIANA School of Medicine and Public Health, Avenida Dom João VI, No. 275, Brotas, 40290-000 Salvador, BA, BrazilBAHIANA School of Medicine and Public Health, Avenida Dom João VI, No. 275, Brotas, 40290-000 Salvador, BA, BrazilIntroduction. Akathisia affects around 18% of patients with bipolar disorder treated with aripiprazole and may worsen when aripiprazole is combined with lamotrigine and antidepressants. Case. This paper reports on two clinical cases involving patients with a diagnosis of mood disorder who developed severe akathisia, anxiety, and suicidal ideation while using a combination of aripiprazole, antidepressants, and lamotrigine. Discussion. We recommend that patients with a mood disorder taking multiple drugs should begin aripiprazole therapy with low doses and be monitored for the development of akathisia, increased anxiety, or suicidal thoughts. The appearance of these limiting side effects requires discontinuation of the drug.http://dx.doi.org/10.1155/2015/419746 |
| spellingShingle | Milena Pereira Pondé Antonio Carlos Cruz Freire Increased Anxiety, Akathisia, and Suicidal Thoughts in Patients with Mood Disorder on Aripiprazole and Lamotrigine Case Reports in Psychiatry |
| title | Increased Anxiety, Akathisia, and Suicidal Thoughts in Patients with Mood Disorder on Aripiprazole and Lamotrigine |
| title_full | Increased Anxiety, Akathisia, and Suicidal Thoughts in Patients with Mood Disorder on Aripiprazole and Lamotrigine |
| title_fullStr | Increased Anxiety, Akathisia, and Suicidal Thoughts in Patients with Mood Disorder on Aripiprazole and Lamotrigine |
| title_full_unstemmed | Increased Anxiety, Akathisia, and Suicidal Thoughts in Patients with Mood Disorder on Aripiprazole and Lamotrigine |
| title_short | Increased Anxiety, Akathisia, and Suicidal Thoughts in Patients with Mood Disorder on Aripiprazole and Lamotrigine |
| title_sort | increased anxiety akathisia and suicidal thoughts in patients with mood disorder on aripiprazole and lamotrigine |
| url | http://dx.doi.org/10.1155/2015/419746 |
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