Neuroprotective effects of curculigoside against Alzheimer’s disease via regulation oxidative stress mediated mitochondrial dysfunction in L-Glu-exposed HT22 cells and APP/PS1 mice

Neuroprotective effects of curculigoside against Alzheimer’s disease via regulation oxidative stress mediated mitochondrial dysfunction in L-Glu-exposed HT22 cells and APP/PS1 mice

Curculigoside (CCG) is a phenolic glycoside compound extracted from the root of a natural plant called Curculigo orchioides Gaertn. In this study, the neuroprotective effect of CCG through oxidative stress mediated mitochondrial dysfunction on L-glutamate (L-Glu)-damaged hippocampal neuron cell line...

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Bibliographic Details
Main Authors: Wenqi Wang, Yidi Qu, Siyu Li, Jinyu Chu, Hongxin Yang, Lirong Teng, Di Wang
Format: Article
Language:English
Published: Tsinghua University Press 2023-07-01
Series:Food Science and Human Wellness
Subjects:
Alzheimer's disease
Curculigoside
Apoptosis
Oxidative stress
Mitochondrial dysfunction
AMPK/Nrf2 signaling
Online Access:http://www.sciencedirect.com/science/article/pii/S2213453022002282
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