Ginsenoside Rh4 inhibits colorectal cancer via the modulation of gut microbiota-mediated bile acid metabolism

Ginsenoside Rh4 inhibits colorectal cancer via the modulation of gut microbiota-mediated bile acid metabolism

Introduction: Dysbiosis of the gut microbiota is emerging as a pivotal factor in the pathogenesis of colorectal cancer (CRC). Ginsenoside Rh4 (Rh4) is an active compound isolated from ginseng with beneficial effects in modulating intestinal inflammation and gut microbiota dysbiosis, but how Rh4 regu...

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Bibliographic Details
Main Authors: Xue Bai, Zhiguang Duan, Jianjun Deng, Zhuo Zhang, Rongzhan Fu, Chenhui Zhu, Daidi Fan
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Journal of Advanced Research
Subjects:
Gut microbiota
Bile acid
Ursodeoxycholic acid
Akkermansia muciniphila
Colorectal cancer
Ginsenoside
Online Access:http://www.sciencedirect.com/science/article/pii/S2090123224002650
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