Evaluation of the antibacterial potential in shoot and root extracts of Eryngium campestre with emphasis on Egyptian ecotype
Abstract The antibacterial potential of Egyptian Eryngium campestre (E. campestre) was evaluated by investigating the growth inhibition of ethanolic shoot and root crude extracts and their solvent fractions against nine bacterial species, revealing a selective differential effect. Phytochemical scre...
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Nature Portfolio
2025-07-01
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| Series: | Scientific Reports |
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| Online Access: | https://doi.org/10.1038/s41598-025-05193-9 |
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| author | Salma Hassan Zaki Dina Ahmed Selim Noha Khalifa Abo Aasy Shacker Helmi |
| author_facet | Salma Hassan Zaki Dina Ahmed Selim Noha Khalifa Abo Aasy Shacker Helmi |
| author_sort | Salma Hassan Zaki |
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| description | Abstract The antibacterial potential of Egyptian Eryngium campestre (E. campestre) was evaluated by investigating the growth inhibition of ethanolic shoot and root crude extracts and their solvent fractions against nine bacterial species, revealing a selective differential effect. Phytochemical screening of crude extracts identified the presence of flavonoids, alkaloids, tannins, saponins, phenols, terpenoids, steroids, and coumarins, suggesting their potential contribution to the observed antibacterial effects. Notably, the ethyl acetate fraction of the shoot and the petroleum ether fraction of the root demonstrated the highest activity, inhibiting the growth of all tested bacteria. Comparative analysis with other ecotypes highlighted variations in their antibacterial potency. These findings position the Egyptian E. campestre ecotype as a promising source for pharmaceutical industry, particularly for developing biocontrol agents against bacterial infectious diseases, including multidrug-resistant strains. |
| format | Article |
| id | doaj-art-b21b6ab6ecc64f0282f0eb48975c3cc7 |
| institution | Kabale University |
| issn | 2045-2322 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj-art-b21b6ab6ecc64f0282f0eb48975c3cc72025-08-20T03:42:25ZengNature PortfolioScientific Reports2045-23222025-07-0115111410.1038/s41598-025-05193-9Evaluation of the antibacterial potential in shoot and root extracts of Eryngium campestre with emphasis on Egyptian ecotypeSalma Hassan Zaki0Dina Ahmed Selim1Noha Khalifa Abo Aasy2Shacker Helmi3Department of Environmental Studies, Institute of Graduate Studies and Research, Alexandria UniversityDepartment of Pharmacognosy, Faculty of Pharmacy, Alexandria UniversityDepartment of Industrial Pharmacy, Faculty of Pharmacy, Alexandria UniversityDepartment of Environmental Studies, Institute of Graduate Studies and Research, Alexandria UniversityAbstract The antibacterial potential of Egyptian Eryngium campestre (E. campestre) was evaluated by investigating the growth inhibition of ethanolic shoot and root crude extracts and their solvent fractions against nine bacterial species, revealing a selective differential effect. Phytochemical screening of crude extracts identified the presence of flavonoids, alkaloids, tannins, saponins, phenols, terpenoids, steroids, and coumarins, suggesting their potential contribution to the observed antibacterial effects. Notably, the ethyl acetate fraction of the shoot and the petroleum ether fraction of the root demonstrated the highest activity, inhibiting the growth of all tested bacteria. Comparative analysis with other ecotypes highlighted variations in their antibacterial potency. These findings position the Egyptian E. campestre ecotype as a promising source for pharmaceutical industry, particularly for developing biocontrol agents against bacterial infectious diseases, including multidrug-resistant strains.https://doi.org/10.1038/s41598-025-05193-9Eryngium campestre ecotypesAntibacterialMulti drug resistantFractionationEthanolic crude extract |
| spellingShingle | Salma Hassan Zaki Dina Ahmed Selim Noha Khalifa Abo Aasy Shacker Helmi Evaluation of the antibacterial potential in shoot and root extracts of Eryngium campestre with emphasis on Egyptian ecotype Scientific Reports Eryngium campestre ecotypes Antibacterial Multi drug resistant Fractionation Ethanolic crude extract |
| title | Evaluation of the antibacterial potential in shoot and root extracts of Eryngium campestre with emphasis on Egyptian ecotype |
| title_full | Evaluation of the antibacterial potential in shoot and root extracts of Eryngium campestre with emphasis on Egyptian ecotype |
| title_fullStr | Evaluation of the antibacterial potential in shoot and root extracts of Eryngium campestre with emphasis on Egyptian ecotype |
| title_full_unstemmed | Evaluation of the antibacterial potential in shoot and root extracts of Eryngium campestre with emphasis on Egyptian ecotype |
| title_short | Evaluation of the antibacterial potential in shoot and root extracts of Eryngium campestre with emphasis on Egyptian ecotype |
| title_sort | evaluation of the antibacterial potential in shoot and root extracts of eryngium campestre with emphasis on egyptian ecotype |
| topic | Eryngium campestre ecotypes Antibacterial Multi drug resistant Fractionation Ethanolic crude extract |
| url | https://doi.org/10.1038/s41598-025-05193-9 |
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