Glucagon-like peptide-1 receptor agonists and type 1 diabetes: a potential game changer?
This mini review explores the increasing prevalence of obesity in type 1 diabetes (T1D) and the challenges patients face in achieving optimal glycemic control with current treatments. It discusses the evidence supporting the use of glucagon-like peptide-1 receptor agonists (GLP-1RA) as potential adj...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2025-01-01
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| Series: | Frontiers in Endocrinology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fendo.2024.1520313/full |
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| author | Ortal Resnick Fernando Bril Fernando Bril Giovanna Beauchamp |
| author_facet | Ortal Resnick Fernando Bril Fernando Bril Giovanna Beauchamp |
| author_sort | Ortal Resnick |
| collection | DOAJ |
| description | This mini review explores the increasing prevalence of obesity in type 1 diabetes (T1D) and the challenges patients face in achieving optimal glycemic control with current treatments. It discusses the evidence supporting the use of glucagon-like peptide-1 receptor agonists (GLP-1RA) as potential adjunctive therapy in T1D to reduce weight and improve insulin resistance. Potential benefits need to be weighed against the risk of hypoglycemia and lack of long-term data. |
| format | Article |
| id | doaj-art-b2188ceb997042498f7d7318b7dc3583 |
| institution | Kabale University |
| issn | 1664-2392 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Endocrinology |
| spelling | doaj-art-b2188ceb997042498f7d7318b7dc35832025-01-21T05:43:36ZengFrontiers Media S.A.Frontiers in Endocrinology1664-23922025-01-011510.3389/fendo.2024.15203131520313Glucagon-like peptide-1 receptor agonists and type 1 diabetes: a potential game changer?Ortal Resnick0Fernando Bril1Fernando Bril2Giovanna Beauchamp3Division of Pediatric Endocrinology and Diabetes, University of Alabama at Birmingham, Birmingham, AL, United StatesDivision of Endocrinology, Diabetes and Metabolism, University of Alabama at Birmingham, Birmingham, AL, United StatesUAB Comprehensive Diabetes Center, University of Alabama at Birmingham, Birmingham, AL, United StatesDivision of Pediatric Endocrinology and Diabetes, University of Alabama at Birmingham, Birmingham, AL, United StatesThis mini review explores the increasing prevalence of obesity in type 1 diabetes (T1D) and the challenges patients face in achieving optimal glycemic control with current treatments. It discusses the evidence supporting the use of glucagon-like peptide-1 receptor agonists (GLP-1RA) as potential adjunctive therapy in T1D to reduce weight and improve insulin resistance. Potential benefits need to be weighed against the risk of hypoglycemia and lack of long-term data.https://www.frontiersin.org/articles/10.3389/fendo.2024.1520313/fullobesityadiposityinsulin resistanceoverweightweight loss |
| spellingShingle | Ortal Resnick Fernando Bril Fernando Bril Giovanna Beauchamp Glucagon-like peptide-1 receptor agonists and type 1 diabetes: a potential game changer? Frontiers in Endocrinology obesity adiposity insulin resistance overweight weight loss |
| title | Glucagon-like peptide-1 receptor agonists and type 1 diabetes: a potential game changer? |
| title_full | Glucagon-like peptide-1 receptor agonists and type 1 diabetes: a potential game changer? |
| title_fullStr | Glucagon-like peptide-1 receptor agonists and type 1 diabetes: a potential game changer? |
| title_full_unstemmed | Glucagon-like peptide-1 receptor agonists and type 1 diabetes: a potential game changer? |
| title_short | Glucagon-like peptide-1 receptor agonists and type 1 diabetes: a potential game changer? |
| title_sort | glucagon like peptide 1 receptor agonists and type 1 diabetes a potential game changer |
| topic | obesity adiposity insulin resistance overweight weight loss |
| url | https://www.frontiersin.org/articles/10.3389/fendo.2024.1520313/full |
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